IMR Press / CEOG / Volume 46 / Issue 5 / DOI: 10.12891/ceog4808.2019

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Case Report
Pulmonary lymphangioleiomyomatosis as an uncommon cause of recurrent early pregnancy loss
Show Less
1 Department of Obstetrics and Gynecology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey
*Correspondence: (S. GUVEN)
Clin. Exp. Obstet. Gynecol. 2019, 46(5), 831–832;
Published: 10 October 2019

Pulmonary lymphangioleimyomatosis (LAM) is a rare disorder characterized by hamartomatous proliferation of smooth muscle within lung parenchyma. LAM occurs only in women and exacerbates with menstruation, estrogen use, and taking oral contraceptives. The effect of pulmonary LAM on recurrent pregnancy loss has not been reported previously. A 28-years-old (gravida 2 parity 0 abortion 2) woman was admitted to the gynecology outpatient clinic because of habitual abortion. The patient had a history of early (one 8-week and another 6-week) pregnancy losses. CT scan showed widespread and varied dimension thin edge cystic lesions extending to about 1 cm in diameter of the largest size observed in all segments of both lungs. All other recurrent pregnancy loss tests were within normal limits, except pulmonary LAM findings on CT scan. Clinicians should keep in mind the diagnosis of pulmonary LAM, in cases with progressive dyspnea (especially in luteal phase of menstruation) and recurrent pregnancy losses.

Habitual abortion
Pulmonary lymphangioleiomyomatosis
Figure 1.
Back to top