IMR Press / CEOG / Volume 46 / Issue 3 / DOI: 10.12891/ceog4698.2019

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Factors for predicting cesarean section during epidural analgesia: a retrospective study
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1 Department of Anesthesia, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China
2 Department of Anesthesia, Department of Anesthesiology Perioperative and Pain Medicine Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, U.S.A.
*Correspondence: (LIN WANG)
Clin. Exp. Obstet. Gynecol. 2019, 46(3), 443–446;
Published: 10 June 2019

Purpose of investigation: To explore the risk factors for cesarean section during trial of labor with epidural analgesia. Materials and methods: A total of 100 parturients who received epidural analgesia were selected for this study. Fifty parturients underwent vaginal deliveries and 50 parturients underwent cesarean sections. Patient-controlled epidural analgesia (PCEA) was carried out with the continuous infusion of 0.125% bupivacaine and 2 mcg/ml fentanyl at 6 ml/h with patient-controlled analgesia (6 ml/time, locked time 15 minutes). Results: The univariate analysis showed a significant difference in the gestational age of parturients between cesarean section and vaginal delivery (p = 0.013). Compared with the parturients in the vaginal delivery group, cesarean section group parturients showed longer interval time from epidural analgesia to cesarean section (p < 0.001), a higher number of analgesia interventions (p < 0.001), higher doses of PCEA (p < 0.001), and higher number of top-ups (p = 0.015). Multivariate analysis revealed that a high gestational age and long interval time were strongly associated with a high possibility of cesarean section during epidural analgesia. Conclusion: High gestational age and long interval time are important risk factors for the prediction of cesarean section during epidural analgesia.

Epidural analgesia
Cesarean section
Vaginal delivery
Figure 1.
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