- Academic Editor
-
-
-
†These authors contributed equally.
Background: For individuals with persistent stable chest pain (SCP) and
a coronary artery calcium score (CACS) of 0, it might be challenging to establish
the best risk assessment method for determining the individuals who will not
benefit from further cardiovascular imaging testing (CIT). Thus, we investigated
the CACS-weighted clinical likelihood (CACS-CL) model in SCP patients with a CACS
of 0. Methods: Thus, to assess SCP, we originally enrolled 14,232
individuals for CACS and coronary computed tomography angiography (CCTA) scans
between January 2016 and January 2018. Finally, patients with a CACS of 0 were
included and followed up until January 2022. According to the established
CACS-CL cutoffs of 15% and 5%, the associations between coronary artery disease
(CAD) and major adverse cardiovascular events (MACEs) in risk groups were
evaluated, alongside the net reclassification improvement (NRI).
Results: Of the 6689 patients with a CACS of 0, the prevalence of CAD
increased significantly (p