Background: Refractory angina is a frequently encountered phenomenon in
patients with coronary artery disease, often presenting therapeutic challenges to
the clinical cardiologist. Novel treatment methods have been explored in this
direction, with the coronary sinus reducer (CSR) being among the most
extensively-investigated. Methods: We conducted a systematic review of
the literature for studies assessing the efficacy of CSR in patients with
refractory angina. The primary endpoints of interest were procedural success and
the improvement in angina according to the Canadian Cardiovascular Society (CCS)
by at least one class. Secondary endpoints were the rate of periprocedural
adverse events, the improvement by at least 2 CCS classes, and the mean change in
CCS class. A random-effects meta-analysis of proportions (procedural success,
improvement by
Announcements
Open Access
Systematic Review
The Efficacy of Coronary Sinus Reducer in Patients with Refractory Angina: A Systematic Review and Meta-Analysis
Panagiotis Theofilis1, Panayotis K Vlachakis1, Marios Sagris1, Emmanouil Mantzouranis1, Athanasios Sakalidis1, Stergios Soulaidopoulos1, Christos Chasikidis1, Evangelos Oikonomou2, Konstantinos Tsioufis1, Dimitris Tousoulis1,*
Show Less
1
1st Cardiology Department, “Hippokration” General Hospital, University of Athens Medical School, 11527 Athens, Greece
2
3rd Cardiology Department, “Sotiria” Regional Hospital for Chest Diseases, University of Athens Medical School, 11527 Athens, Greece
*Correspondence: drtousoulis@hotmail.com (Dimitris Tousoulis)
Rev. Cardiovasc. Med. 2024, 25(3), 82;
https://doi.org/10.31083/j.rcm2503082
Submitted: 22 October 2023 | Revised: 16 December 2023 | Accepted: 22 December 2023 | Published: 4 March 2024
Copyright: © 2024 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract
Keywords
coronary sinus reducer
refractory angina
coronary artery disease
Figures
Fig. 1.