Background: Some patients with hypertrophic obstructive cardiomyopathy
(HOCM) still exhibit systolic anterior motion (SAM) and mitral regurgitation (MR)
even after undergoing an isolated ventricular septectomy. Currently, there are
disputes regarding whether to perform a mitral valve intervention and which type
of operation is more effective. Methods: By searching PubMed, Cochrane,
Embase, Web of Science, FDA.gov, and ClinicalTrials.gov, as well as other
resource databases, we obtained all articles published before December 2022 on
ventricular septal myectomy combined with mitral valve intervention for
hypertrophic cardiomyopathy. Demographic information and outcome variable data
were extracted from 10 screened studies on ventricular septal resection combined
with mitral valve repair. The risk of bias was assessed using methodological
index for non-randomized studies (MINORS). Student’s t-test was used for
comparisons of continuous variables, and the chi-square or Fisher’s exact test
was used for dichotomous variables. A total of 692 patients across 10 studies
were analyzed. Results: There were 5 (0.7%) deaths in the perioperative
period. The average cardiopulmonary bypass time was 64.7
Announcements
Open Access
Systematic Review
Septal Myectomy and Subvalvular Repair in Hypertrophic Cardiomyopathy, a Systematic Review and Pooled Analysis
Show Less
1
Division of Cardiothoracic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030 Wuhan, Hubei, China
2
Key Laboratory of Organ Transplantation, Ministry of Education, 430010 Wuhan, Hubei, China
3
NHC Key Laboratory of Organ Transplantation, 430073 Wuhan, Hubei, China
4
Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, 430010 Wuhan, Hubei, China
*Correspondence: ruilee_tj@126.com (Rui Li)
Rev. Cardiovasc. Med. 2023, 24(9), 268;
https://doi.org/10.31083/j.rcm2409268
Submitted: 23 February 2023 | Revised: 17 March 2023 | Accepted: 31 March 2023 | Published: 22 September 2023
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract
Keywords
hypertrophic cardiomyopathy
mitral valve insufficiency
subvalvuar repair
septal myectomy
Figures
Fig. 1.