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- Academic Editor
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Background: The visceral-adiposity-tissue index (VATI) and the
triglyceride-glucose (TyG) index were found to be correlated with an increased
risk of cardiovascular events. However, data concerning the association between
the visceral adiposity/TyG indexes and the complication of new-onset
postoperative atrial fibrillation (POAF), especially in patients who had just
undergone off-pump coronary artery bypass grafting (OPCABG), are rare. We
explored the predictive value of the computed-tomography-based VATI and the TyG
index on new-onset POAF after OPCABG. Methods: This study used
longitudinal data from the cohort of 542 participants who underwent OPCABG in
Beijing Anzhen Hospital since June 2017. The predictive relevance of the VATI and
TyG index were evaluated through Cox proportional hazards models and receiver
operating characteristic (ROC) curves. The dose‒response relationship of the VATI
and TyG index with new-onset POAF was analyzed by multiple-adjusted spline
regression models, and sensitivity analysis was used to explore the stability of
our findings. Results: The analysis found that the highest tertile of
VATI [hazard ratio (HR) 2.58, 95% confidence interval (CI) 1.12–3.45; p = 0.01] and TyG index (HR 2.88, 95% CI 1.76–4.71; p = 0.01) were
significantly associated with new-onset POAF compared to the lowest tertile after
full adjustment for age, sex, body mass index, c-reactive protein levels,
diabetes, emergency operation, New York Heart Association (NYHA) III–IV, and left
atrial diameter. The area under the ROC curve (AUC) was 0.897 (p