IMR Press / RCM / Volume 23 / Issue 2 / DOI: 10.31083/j.rcm2302074
Open Access Systematic Review
Exercise-based cardiac rehabilitation after myocardial revascularization: a systematic review and meta-analysis
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1 Department of Biological Sciences, University of the State of Minas Gerais – Carangola Unit, 36800-000 Carangola, Brazil
2 Department of Physiology and Biophysics, Institute of Biological Sciences, Federal University of Minas Gerais, 31270-901 Belo Horizonte, Brazil
3 Department of Physical Education, State University of Minas Gerais – Divinópolis Unit, 35501-170 Divinópolis, Brazil
4 Faculty of Medicine, University of Rio Verde, 74923-250 Aparecida de Goiânia, Brazil
5 Department of Physical Education, Federal University of Minas Gerais, 31270‑901 Belo Horizonte, Brazil
*Correspondence: (Cândido Celso Coimbra)
These authors contributed equally.
Academic Editor: Peter A. McCullough
Rev. Cardiovasc. Med. 2022, 23(2), 74;
Submitted: 14 December 2021 | Revised: 20 January 2022 | Accepted: 24 January 2022 | Published: 22 February 2022
(This article belongs to the Special Issue Cardiac rehabilitation)
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.

Background: The present study aimed to analyze the effects of exercise-based cardiac rehabilitation (CR) on physical performance after myocardial revascularization. In addition, we compared the type and duration of exercise-based CR protocols to determine which ones produced the best performance improvements. Methods: This systematic review and meta-analysis was conducted and reported in accordance with PRISMA statement. A systematic search of PubMed, Web of Science, SPORTDiscus and ProQuest, was performed in July 2020. Studies that met the following criteria were included: (i) participants submitted to myocardial revascularization (i.e., coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI)), (ii) participants submitted to exercise-based CR, and (iii) participants submitted to protocols for assessing physical performance before and after the exercise-based CR. Results: Thirteen and eleven studies evaluating the effects of exercise-based CR after myocardial revascularization were included in the systematic review and meta-analysis, respectively. Exercise-based CR increased physical performance after myocardial revascularization (mean effect size (ES) 0.75; 95% confidence interval (CI) 0.62, 0.88), particularly when aerobic (ES 0.85; 95% CI 0.68, 1.01) and combined training (ES 1.04; 95% CI 0.70, 1.38) lasting 8–12 weeks (ES 1.20; 95% CI 0.87, 1.53) was prescribed. Conclusions: The present systematic review and meta-analysis indicates that exercise-based CR increases physical performance after myocardial revascularization. The prescription of physical training for these patients should emphasize aerobic and combined training lasting at least 8–12 weeks, which is more effective in improving physical performance. Impact: Our findings demonstrate the effectiveness of physical training in improving physical performance after myocardial revascularization.

myocardial revascularization
exercise-based cardiac rehabilitation
physical training
Fig. 1.
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