Frequency of ST-segment elevation myocardial infarction, non-ST-segment myocardial infarction, and unstable angina: results from a Southwest Chinese Registry

Si-Yi Li^1,†, Ming-Gang Zhou^1,†, Tao Ye¹, Lian-Chao Cheng¹, Feng Zhu¹, Cai-Yan Cui¹, Yu-Mei Zhang¹, Lin Cai^1,*

Show Less

¹ Department of Cardiology, Affiliated Hospital of Southwest Jiaotong University, The Third People’s Hospital of Chengdu, 82 Qinglong St. Chengdu, 610015 Sichuan, P. R. China

^*Correspondence: cailinwm@163.com (Lin Cai)
^†These authors contributed equally.
Academic Editor: Peter A. McCullough

Rev. Cardiovasc. Med. 2021, 22(1), 239–245; https://doi.org/10.31083/j.rcm.2021.01.103

Submitted: 25 May 2020 | Revised: 14 October 2020 | Accepted: 21 October 2020 | Published: 30 March 2021

This is an open access article under the CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).

Abstract

The burden of cardiovascular disease is predicted to escalate in developing countries. The aim of this study is to assess the characteristics, management strategies and outcomes of the patients with acute coronary syndrome (ACS) who were admitted to hospitals under the chest pain center mode in southwest P. R. China. Adults hospitalized with a diagnosis of ACS were enrolled in the retrospective, observational registry between January 2017 and June 2019 at 11 hospitals in Chengdu, P. R. China. The collected data included the patients’ baseline characteristics, clinical management and in-hospital outcomes. After Statistical analysis, (1) A total of 2857 patients with ACS, among which 1482 have ST-segment elevation myocardial infarction (STEMI), 681 have non-STEMI (NSTEMI) and 694 have unstable angina (UA) were enrolled in the study. (2) 61.3% of the ACS patients received reperfusion therapy. More patients with STEMI underwent percutaneous coronary intervention (PCI) compared with NSTEMI/UA patients (80.6% vs. 38.8%, P $<$ 0.001), while thrombolytics were administered in only 1.8% of STEMI patients. (3) The median time from symptoms to hospital was 190 min (IQR 94-468) in STEMI, 283 min (IQR 112-1084) in NSTEMI and 337 min (IQR 97-2220) in UA (P $<$ 0.001), and the door-to-balloon time for primary PCI (pPCI) was 85 min (IQR 55-121) in STEMI. (4) The in-hospital outcomes for STEMI patients included death (8.1%) and acute heart failure (22.6%), while the outcomes for those with NSTEMI and UA were better: death (4.0% and 0.9%, P $<$ 0.001) and acute heart failure (15.3% and 9.9%, P $<$ 0.001). (5) Antiplatelet drugs, lipid-lowering drugs, $\beta$ -blockers and angiotensin-converting enzyme inhibitors (ACEI) /angiotensin receptor blockers (ARB) were used in about 98.3%, 95.0%, 67.7% and 54.3% of the ACS patients, respectively. Therefore, the management capacity in Chengdu has relatively increased compared with previous studies, but important gaps still exist compared with developed countries, especially regarding the management of the NSTEMI/UA patients.

Keywords

Acute coronary syndrome

Clinical characteristics

Percutaneous coronary intervention

In-hospital outcomes

Figures

Fig. 1.

Previous article in this issue

Next article in this issue

Rev. Cardiovasc. Med. Print ISSN 1530-6550 Electronic ISSN 2153-8174