The antibacterial activity of the extracts of myrtle black and white leaves was determined. By the increase of the concentration of the extracts, antibacterial activity also increased. The most effective extract was the methanol extract of the leaves of the white myrtle against S. aureus. While, effect of ethyl acetate extracts of white and black myrtle leaves were very low to S. aureus and P. vulgaris, methanol extracts of the leaves of the black myrtle inhibited the growth of it. Acetone extracts of white and black myrtle leaves were very effective against P. mirabilis. B. cereus was most resistant to ethyl acetate extract of myrtle leaves, but the reduction effect of methanol extract was very high.