Dear Colleagues,

The process of vascular remodeling has gained more and more attention in recent years. This term comprises complex disease-associated changes within the vessel wall and the perivascular space not only on the cellular level but also within the vascular extracellular matrix with a distinct structural and functional reorganization. Vascular remodeling is a pathogenetic key mechanism not only for frequently occurring disorders like atherosclerotic cardiovascular disease or arterial hypertension but also for a variety of other pathologies, e.g., inflammatory rheumatic diseases (especially vasculitis), allograft vasculopathy following organ transplantation or even hereditary disorders. Despite the complexity and disease-specificity of vascular remodeling, the identification and detailed investigation of common mechanisms might pave the way for the development of novel diagnostic approaches or even targeted treatment strategies.

For the Special Issue “New Frontiers in Vascular Remodeling”, researchers in the field are encouraged to submit both original research manuscripts and review articles. The original contributions should report on novel mechanistic, translational or clinical insights into prevention, diagnosis or treatment of vascular remodeling covering the whole spectrum of associated disorders. Review articles should focus on advances in the field in a systematic way, preferentially structured according to underlying diseases or certain sub-processes of vascular remodeling.

Prof. Dr. Marcus Franz and Dr. Alexander Pfeil

Guest Editors