IMR Press / CEOG / Volume 50 / Issue 4 / DOI: 10.31083/j.ceog5004091
Open Access Original Research
Sugar-Sweetened Beverage Use Pattern in the First Trimester is Associated with Gestational Diabetes Mellitus
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1 Department of Obstetrics and Gynecology, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, 807 Kaohsiung, Taiwan
2 Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 807 Kaohsiung, Taiwan
3 Department of Public Health, College of Health Science, Kaohsiung Medical University, 807 Kaohsiung, Taiwan
4 Center of Cancer Research, Kaohsiung Medical University, 807 Kaohsiung, Taiwan
*Correspondence: Tefu.chan@msa.hinet.net (Te-Fu Chan)
These authors contributed equally.
Clin. Exp. Obstet. Gynecol. 2023, 50(4), 91; https://doi.org/10.31083/j.ceog5004091
Submitted: 22 December 2022 | Revised: 8 March 2023 | Accepted: 9 March 2023 | Published: 24 April 2023
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract

Background: Sugar-sweetened beverage (SSB) is known to increase risks for many health problems in the general population, but its association with gestational diabetes mellitus (GDM) is rarely discussed. Consumption amount of SSB could be subjected to recall biases and estimation errors, whereas psychological dependence using a standardized assessment tool would provide more persistent and objective measurements. Therefore, we hypothesize that desire of SSB may play a role in developing GDM. Methods: This prospective cohort study recruited 183 pregnant women, who answered self-describing questionnaires designed to depict SSB use behaviors. The desire to drink SSBs was assessed using the modified Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for substance use disorder (SUD), with questions specific for SSB use. All participants received a 75-gram oral glucose tolerance test during 24th–28th weeks of gestation to screen for GDM. Results: Age, body mass index, and SSB-related SUD DSM-5 items were significant predictive factors of GDM, with odds ratios of 1.112 (95% confidence interval 1.018–1.214), 1.208 (95% confidence interval 1.079–1.353), and 1.338 (95% confidence interval 1.077–1.664), respectively. SUD DSM-5 scores positively correlate with education level (p = 0.046), frequency of dining out (p = 0.028), sedentary lifestyle (p = 0.001), and negatively with water intake amount (p = 0.033). Conclusions: The current study is the first to find a positive association between SSB intake pattern and GDM risk. Specifically, every SSB-related DSM point scored increases GDM risk by 33%, which did not necessarily reflect on the reported SSB consumption amount. To offer useful and specific behavioral advices, decreasing frequencies of dining out, increasing exercises and encouraging plain water intake might be helpful.

Keywords
gestational diabetes
sugar-sweetened beverage
sugar consumption
high risk pregnancy
Funding
MOST 107- 2314-B-037-064-MY3/Ministry of Science and Technology
MOST 111-2314-B-037-074-/Ministry of Science and Technology
KMUH 106-6R37/Kaohsiung Medical University Hospital
KMUH 107-7R37/Kaohsiung Medical University Hospital
KMUH 108-8R43/Kaohsiung Medical University Hospital
KMUH 109-9R43/Kaohsiung Medical University Hospital
KMUH110-0M44/Kaohsiung Medical University Hospital
KMUH111-1R39/Kaohsiung Medical University Hospital
KMUH 11010/Kaohsiung Medical University Hospital
KMUH-S11007/Kaohsiung Medical University Hospital
KMU-TC108A04-0/Kaohsiung Medical University
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