- Academic Editor
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†These authors contributed equally.
Background: One of the characteristics that is directly linked to
polycystic ovary syndrome (PCOS) is body mass index (BMI), and there have been
numerous studies that are pertinent to PCOS patients with high BMI. However,
further research is needed to determine the precise impacts of normal BMI on PCOS
patients’ metabolism and chances of becoming pregnant. Achieving a normal BMI may
enhance glucose metabolism and lower the risk of gestational diabetes in pregnant
PCOS women. By examining the reproductive results of PCOS patients with normal
BMI, this study offers fresh suggestions for the management and alleviation of
clinical symptoms in PCOS patients. Methods: From January 1, 2021 to
April 30, 2022, 133 in vitro fertilization/intracytoplasmic sperm
injection (IVF/ICSI) cases with normal body mass index were enrolled in the
Reproductive Medical Center of Hainan Women and Children’s Medical Centre,
including 77 PCOS patients with normal BMI and 46 non-PCOS patients with normal
BMI, the ovulation induction regimen was used as an antagonist regimen, and the
waist circumference, body mass index, follicle-stimulating hormone (FSH),
luteinizing hormone (LH), LH/FSH, anti-Mullerian hormone (AMH), blood lipids,
homeostasis model assessment of insulin resistance (HOMA-IR), gonadotropin (Gn) dosage between the two groups were
compared, Gn days of use, number of eggs obtained, normal fertilization rate,
normal cleavage rate, number of available embryos, number of high-quality
embryos, embryo implantation rate, clinical pregnancy rate and other indicators.
Results: The endocrine situation between the two groups showed that the
AMH, LH value, LH/FSH value, fasting insulin and HOMA-IR of PCOS group (group 1)
were significantly higher than control group (group 2), and the data between the
two groups were extremely significant (p