IMR Press / CEOG / Volume 49 / Issue 3 / DOI: 10.31083/j.ceog4903066
Open Access Original Research
Paracervical block in laparoscopic hysterectomy for postoperative pain control: a randomized, multi-center, double-blind, placebo-controlled trial
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1 Department of Obstetrics & Gynecology, Wonju Severance Christian Hospital, 26426 Wonju, South Korea
2 Department of Obstetrics & Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 03181 Seoul, South Korea
3 Department of Obstetrics & Gynecology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 03181 Seoul, South Korea
4 Department of Obstetrics & Gynecology, Kangnam Sacred-Heart Hospital, Hallym University Medical Center, Hallym University College of Medicine, 07441 Seoul, South Korea
*Correspondence: (Taejong Song)
Academic Editor: Christos Iavazzo
Clin. Exp. Obstet. Gynecol. 2022, 49(3), 66;
Submitted: 9 June 2021 | Revised: 5 July 2021 | Accepted: 9 July 2021 | Published: 9 March 2022
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.

Background: To determine the effect of a paracervical block in laparoscopic hysterectomy on postoperative pain relief. Method: A total of 86 patients scheduled for total laparoscopic hysterectomy for benign gynecologic diseases were randomly assigned to the experimental group (n = 43) and the control group (n = 43). Patients were received a paracervical injection that was either 10 mL of 0.5% bupivacaine with 1 : 200,000 epinephrine or 10 mL of normal saline. The primary outcome was the postoperative pain score which was assessed using a visual analog scale at 2, 4, 6, 8, and 12 hours after surgery. The secondary outcome was the postoperative rescue analgesic requirement within 12 hours after surgery. Results: Baseline characteristics were similar in both groups. Postoperative pain scores did not significantly differ between groups. Rescue analgesia requirements were also statistically similar in both groups. Conclusion: Adding a paracervical block with preemptive local analgesia in patients undergoing laparoscopic hysterectomy did not reduce postoperative pain and postoperative rescue analgesia requirements.

Paracervical block
Fig. 1.
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