IMR Press / CEOG / Volume 45 / Issue 6 / DOI: 10.12891/ceog4465.2018

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Case Report

Uncomplicated cervical pregnancy treated with new combined regimen of RU-486 and methotrexate- a solution to improve results for conservative management

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1 Department of Obstetric and Gynecology, University of Medicine and Pharmacy Gr T Popa, Iasi, Romania
2 Department of Human Anatomy, University of Medicine and Pharmacy Gr T Popa, Iasi, Romania
Clin. Exp. Obstet. Gynecol. 2018, 45(6), 957–958; https://doi.org/10.12891/ceog4465.2018
Published: 10 December 2018
Abstract

The cervical pregnancy is a rare type of ectopic pregnancy, with less than a 1% incidence, but has a high complication rate. Case Report: The authors present a case of a patient with a seven-week cervical pregnancy with fetal heart beat present. They used a conservative management with methotrexate 1 mg/kg body weight associated to RU-486 200 mg, with methotrexate dose repeated on day 5, which resulted in no radical intervention needed. The case evolution had a two-week normalization of ultrasound and beta hCG aspect. Conclusion: This regimen could be, if confirmed, a solution to increase the efficiency of conservative management in cervical pregnancy.

Keywords
Methotrexate
RU-486
Cervical pregnancy
Conservative management
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