IMR Press / CEOG / Volume 44 / Issue 3 / DOI: 10.12891/ceog3245.2017

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research
Cytogenetic analysis of 10,286 cases with male infertility
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1 School of Public Health, Shandong University, Jinan, China
2 Reproductive Hospital Affiliated to Shandong University, Jinan, China
Clin. Exp. Obstet. Gynecol. 2017, 44(3), 392–394;
Published: 10 June 2017
Purpose: Chromosome analysis of 10,286 cases with male infertility and to discuss the genetic causes of male infertility. Materials and Methods: 10,286 patients with azoospermia and oligoasthenozoospermia were collected in the present center from January 2009 to January 2013.Peripheral blood lymphocyte culture and chromosome analysis were performed. Results: In all the 10,286 cases with azoospermia and oligoasthenozoospermia, 8,401 cases showed normal karyotype, 538 cases had chromosome polymorphism, accounting for 5.2% and 1,378 cases had chromosomal abnormalities with a frequency of 13.4%; Conclusions: Genetic factors are closely related to the occurrence of azoospermia and oligoasthenozoospermia, and chromosome analysis in patients with male infertility is necessary.
Male infertility
Chromosomal abnormality
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