IMR Press / CEOG / Volume 44 / Issue 2 / DOI: 10.12891/ceog3283.2017

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research
Changes in irisin levels in patients with hyperemesis gravidarum
Show Less
1 Firat University, School of Medicine, Firat Medical Center, Department of Obstetrics and Gynecology, Elazig, Turkey
2 Special In Vitro Lab, Department of Biochemistry, Elazig, Turkey
Clin. Exp. Obstet. Gynecol. 2017, 44(2), 200–202;
Published: 10 April 2017

Purpose: The aim of this study was to compare levels of serum irisin in hyperemesis gravidarum (HG) patients to healthy gravidas. Materials and Methods: Twenty pregnant women with hyperemesis gravidarum (Group 1) and 20 healthy pregnant women (Group 2) all of similar ages, body mass index, and all at similar pregnancy development comprised the study cohort. Fasting serum samples were obtained and measured for irisin levels. Comparisons between groups were done by Mann Whitney U (MWU) test and p < 0.05 was considered as statistically significant. Results: All the patients in groups 1 and 2 were primigravid and age, gestational week, and body mass index values were similar. No statistically significant difference were present among these parameters (p > 0.05, MWU test). The plasma irisin concentrations in group 1 were significantly higher (irisin (average ±S D): 116.9 ± 32.3 ng/ml vs. 87.7 ± 26.2 ng/ml) compared to the control group. Conclusion: This study suggests a possible role of irisin, which might be involved in the pathology of HG.
Hyperemesis gravidarum
Back to top