IMR Press / CEOG / Volume 43 / Issue 2 / DOI: 10.12891/ceog2080.2016

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
In vitro fertilization outcomes in obese women under and above 35 years of age
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1 Department of Obstetrics and Gynecology Clinic, Haydarpaşa Numune Teaching Hospital, Istanbul
2 Department of Obstetrics and Gynecology, Kocaeli University, Faculty of Medicine, Kocaeli (Turkey)
Clin. Exp. Obstet. Gynecol. 2016, 43(2), 233–237; https://doi.org/10.12891/ceog2080.2016
Published: 10 April 2016
Abstract

Purpose: To explore the impact of obesity on in vitro fertilization (IVF) outcomes and comparing the results with regards to age groups. Materials and Methods: This retrospective cohort recruited 780 women that underwent IVF. Women with polycystic ovarian syndrome (PCOS) were excluded from the study. Women under and above 35 years were categorized into three groups as normal weight, overweight, and obese. The main outcome measures were ovarian response, oocyte maturity, and clinical pregnancy rates. Results: Despite oocyte count and fertilization rate that decreased in both younger and older obese women, this difference was not statistically significant. After age matched-normal weight controls, the clinical pregnancy rates were significantly decreased in older obese women. On the other hand, poor ovarian response observed significantly in young obese women without effect on pregnancy rates. Conclusion: These results suggested that obesity in young and old women has different outcomes and different steps of IVF process may be affected.
Keywords
BMI
Obesity
IVF
ICSI
Ovarian response
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