IMR Press / CEOG / Volume 41 / Issue 2 / DOI: 10.12891/ceog16582014

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Case Report
Successful rescue hysteroscopic resection of a cervical ectopic pregnancy previously treated with methotrexate with no combined safety precautions
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1 Institute of Maternal and Child Health, IRCCS “Burlo Garofolo”, Trieste
2 University of Trieste, Trieste
3 Doctoral School in Reproduction and Developmental Sciences, University of Trieste, Trieste (Italy)
Clin. Exp. Obstet. Gynecol. 2014, 41(2), 214–216; https://doi.org/10.12891/ceog16582014
Published: 10 April 2014
Abstract

Background: Cervical pregnancy (CP) is a life-threatening condition that represents less than one percent of all ectopic pregnancies. Transvaginal sonography (TVS) is the gold standard for an accurate diagnosis. For hemodinamically stable women the available treatments involve a medical therapy, alone or in combination with interventional measures (hysteroscopy, angiographic embolization or laparoscopic ligation of uterine arteries). Materials and Methods: The authors describe a CP unsuccessfully treated with methotrexate (MTX), but resolved with hysteroscopy. Case Report: A nulliparous woman arrived with low abdominal pain without vaginal bleeding at six weeks of amenorrhea. TVS revealed a gestational sac implanted in the isthmic cervical region, with a serum β-hCG of 1,100 mUI/ml, that raised to 4,274 mUI/ml in a week, despite one intrasaccular-MTX injections and two systemic doses. The authors arranged for a hysteroscopic resection with no previous dilatation of the cervix. They did not adopt any safety precautions to their procedure. Conclusion: It is difficult to define the exact role of hysteroscopy regarding CP. Despite some authors dispute on its complementary function to MTX, the authors believe that it could be used as a rescue method in case of MTX failure. The final aims of a proper management are to minimize the risk of haemorrhage and preserve women’s fertility.
Keywords
Cervical ectopic pregnancy
Methotrexate
Hysteroscopy
Fertility
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