IMR Press / CEOG / Volume 40 / Issue 3 / pii/1630388310985-1061295395

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Case Report
Mild increases in serum FSH in late follicular phase increases the risk of the luteinized unruptured follice: case report
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1 Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology Division of Reproductive Endocrinology & Infertility, Camden, NJ The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology Division of Reproductive Endocrinology & Infertility, Camden, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2013, 40(3), 433–434;
Published: 10 September 2013
Abstract

Purpose: To find a case that will support the concept that mild elevation of serum follicle stimulating hormone (FSH) levels in late follicular phase may interfere with the release of the oocyte from the follicle. Materials and Methods: Oocyte release was determined in a woman in a complete natural cycle vs cycles where a boost of very low dose FSH was given, human chorionic gonadotropin (hCG) 10,000 units or leuprolide acetate 1 mg every 12 hours x two doses was given in FSH stimulated cycles. Results: Oocyte release occurred in all natural cycles vs none of the mildly stimulated cycles. Conclusions: Mild changes in the FSH level in the late luteal phase may affect the production of certain FSH dependent factors needed to release the oocyte.
Keywords
Luteinized unruptured follicle syndrome
Gonadotropin
Human chorionic gonadotropin
Leuprolide acetate
Natural cycle
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