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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
About 13% of women may have the wrong method of oocyte insemination when undergoing in vitro fertilization by failure to evaluate the abnormal hypo-osmotic swelling test score
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The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2011, 38(1), 21–23;
Published: 10 March 2011
Abstract
Purpose: To determine the percentage of males with a low hypoosmotic swelling (HOS) test score in couples having in vitro fertilization- embryo transfer (IVF-ET) where the male partner had normal motile densities and no antisperm antibodies. Methods: The results were also analyzed according to the percentage of HOS scores < 50% when morphology using strict criteria was ≤ 4% or > 4%. A retrospective review was performed. Results: There were 250 subnormal HOS scores out of 1993 otherwise normal semen specimens. Conclusions: 12.5% of couples would have had conventional oocyte inseminations rather than ICSI if the HOS test had not been not performed (it is rarely performed by other IVF centers). Without ICSI expected live delivered pregnancy rates would be close to zero for males with low HOS tests < 50%. Intracytoplasmic sperm injection allows pregnancy rates almost as good as completely normal sperm.;">
Keywords
Hypoosmotic swelling test
Intracytoplasmic sperm injection
Conventional oocyte insemination
Implantation defects