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The effect of blastomere number on embryo survival upon freezing/thawing
1 The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2009, 36(4), 209–209;
Published: 10 December 2009
Purpose: To determine if the blastomere number of embryos at the time of freezing is related to its quality post-thaw. Methods: A retrospective cohort analysis of frozen/thawed embryos. Only multi-cell embryos were used for this study. If an embryo was of good quality it would either be transferred or re-frozen. Results: There did not appear to be any trend for a lower percentage of good quality embryos with fewer numbers of blastomeres. Conclusions: Though 4-cell embryos have a markedly lower implantation potential upon fresh embryo transfer compared to 6-8-cell embryos, this is not reflected in their ability to survive freeze-thawing.