IMR Press / CEOG / Volume 34 / Issue 3 / pii/2007050

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report

Long-term personalized GnRH agonist therapy without estrogen supplementation for recurrent endometriotic catamenial pneumothorax - case report

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1 Department of Obstetrics and Gynecology, Wakayama Medical University, Wakayama (Japan)
Clin. Exp. Obstet. Gynecol. 2007, 34(3), 179–181;
Published: 10 September 2007

A patient with diaphragmatic endometriosis who showed immediate relapse following radical thoracoscopic surgery received per­sonalized GnRH agonist (GnRHa) therapy. GnRHa depots were subcutaneously injected by modulating injection intervals according to serum estradiol and LH levels in order to maintain long-term amenorrhea without any adverse effects. A leuprolide acetate depot was injected 24 times for 34 months. Therefore, so far, 1.88 mg of leuprolide acetate depot have been injected every seven weeks to achieve a stable endocrine condition with 15-30 pg/mL serum estradiol, 3-10 JU/Iserum LH, and 7-15 JU/Iserum FSH.

GnRH aonist
Leuprolide acetate
Catamenial pneumothorax
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