Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Hormonal reproductive status of women at menopausal transition compared to that observed in a group of midreproductive-aged women
Objective: To compare the serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), estradiol (E2), testosterone (T) and dehydroepiandrosterone sulfate (DHEA-S) in perimenopausal women to the levels of the same reproductive hormones in younger women. Methods: This was a case control study which compared the hormonal status (circulating levels of FSH, LH, PRL, T, E2, DHEAS) between women at menopausal transition and younger midreproductive-aged controls. The t-test for independent samples was used. Results: FSH, LH and E2 were higher, and T and DHEA-S were lower in perimenopausal women. Conclusion: The reproductive hormonal patterns in perimenopausal women favor a relatively hypergonadotropic hyperestrogenic milieu.