Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Relationship of early follicular phase sera follicle stimulating hormone and luteinizing hormone levels as measured by a radioimmunoassay and an enzyme-linked immunosorbent assay to number of oocytes retrieved
A study was performed to see if the level of serum follicle stimulating hormone(FSH) or luteinizing hormone (LH) obtained in the early follicular phase could predict the number of oocytes retrieved following in vitro fertilization(IVF). For each patient the sera FSH and LH were measured by both an enzyme-linked immunosorbent assay (ELISA) and a radio immuno-assay(RIA) method. With the ELISA method when early follicular phase serum FSH was ≤ to the group median (9.0 mIU/mL) 165 oocytes were retrieved vs 6.7 when FSH was greater than the median. Comparable values using the median of the RIA assay were 17.5 vs 8.1 oocytes. Similar analysis for serum LH failed to show any relationship between baseline LH and the number of oocytes retrieved. This study thus demonstrates that at least one non-isotopic method is equal to a specific RIA method in distinguishing good from average or poor responders.