IMR Press / CEOG / Volume 19 / Issue 4 / pii/1634202876971-1751902876

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research
Iron balance in pregnancy in relation to anemia
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1 Clinica Ostetrica e Ginecologica, dell’Universita di Siena
2 Clinica Ostetrica e Ginecologica, dell’Universita di Padova
Clin. Exp. Obstet. Gynecol. 1992, 19(4), 218–221;
Published: 10 December 1992
Abstract

Blood levels of iron, transferrin and ferritin varied in the course of pregnancy (6th to 42nd week) in 136 women. Analysis of variance showed that the factor “weeks of pregnancy” (< or = 27 or > 27 weeks) was correlated differently with the variables “ferritin” and “iron” according to the presence or absence of anemia (Hb < or = or > or = 11 g/dL). In anemic women the correlation was significant (F-ratio = 5.90; P = 0.018) for iron (which decreased from initial low level until term) but not ferritin, whereas in non-anemic women the correlation was significant (F-ratio = 13.306; P = 0.0006) for ferritin (which decreased to less than 20 micrograms/ml around the 34th week) but not iron. In both anemic and non anemic subjects, transferrin levels increased with weeks of pregnancy. It is concluded that towards the end of pregnancy, some decrease in ferritin (> or = 15 micrograms/ml) is physiological, and in the absence of anemia (Hb > 11 g/dl) iron supplements are not necessary.
Keywords
Pregnancy
Anemia
Iron balance
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