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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Changes in plasmaconcentration of ANP and aldosterone in normal pregnancy and pregnancy complicated by pre-eclampsia
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1
Department of obstetrics and gynecology, Hvidrove Hospital, University of Copenhagen, Denmark
2
Department of Medical physiology C, Panum -Institute, University of Copenhagen, Denmark.
Clin. Exp. Obstet. Gynecol. 1991, 18(3), 185–189;
Published: 10 September 1991
Abstract
Changes in plasmaconcentration of ANP in normal pregnancy and pregnancy complicated by pre-eclampsia were examined and compared to non-pregnant controls. The maternal plasma concentration increased gradually during normal pregnancy but values did not deviate significantly from non-pregnant women. A further increase was demonstrated post partum. In pre-eclampsia maternal plasma ANP levels increased significantly compared with normal gravida at the same gestational age and non-pregnant controls. After delivery ANP decreased significantly. Non correlation between ANP and aldosterone were found in either normal pregnancy nor pregnancy complicated by pre-eclampsia. It is not yet clear how important ANP is for the regulation of blood pressure and sodium and water balance during normal pregnancy and pregnancy complicated by pre-eclampsia.