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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Natural killer cells and Tac antigen in the hypertension of pregnancy
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1
Department of Obstetrics and Gynecology University of Ancona (Italy)
2
Immunology and Cytology Centres, Gerontol. Res. Dept. INRCA - Ancona (Italy)
Clin. Exp. Obstet. Gynecol. 1990, 17(1), 13–15;
Published: 10 March 1990
Abstract
Of the immunological alterations in pregnancy hypertension were studied peripheral blood lymphocyte subpopulation in normal and hypertensive pregnancies by means of monoclonal antibodies. In pregnant women with hypertension an increase was found in NK activity. It was also shown that an increase in circulating T cells expressing Tac antigen occurred in women with pregnancy hypertension. These preliminary data on Tac antigen suggest that there is an activation of Leu 3 cells; which may introduce the concept of Leu 3 activity like NK activity. Further studies on this subject could explain that the concept of Leu 3 activity is correct.
Keywords
hypertension
NK activity
Tac antigen