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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Case Report
Steriological analysis of peritumoral lymph nodes in patients operated for cervical and endometrial cancer after being treated with thymostimulin
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Center for the Study of and Fight against Tumours, General Hospital - Vicenza
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Obstetrics and Gynaecology Division of Schio Hospital (Vicenza Province)
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ULSS no. 8, Vicenza (Italy)
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Macroscopical and Microscopical Pathological Anatomy - 2nd Chair, Siena University (Italy)
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ULSS no. 6, Schio, Vicenza (Italy)
Clin. Exp. Obstet. Gynecol. 1989, 16(4), 134–135;
Published: 10 December 1989
Abstract
We have evaluated by means of steriological analysis the dimensions of the lymph node functional areas (cortical, medullary, paracortical, histiocytosis of the sinuses, germinal centers) m regional lymph nodes of women with cervical ancer (15 women) and endometrial carcinoma (6 women) in 1st and IInd stage, treated 8 days before surgery with a dose of 1-1,5 mg/kg of body weight of thymostimulin directly into the uterine cervix. 4 women with cervical and endometrial cancer (stages I and II) and treated with the same doses of physiological saline solutions were used as controls. The quantitative results show that in the lymph nodes of women treated with thymostimulin there is a statistically significant marked increase, (P < 0.001), of the paracortical areas.