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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
A double blind controlled trial to study the effects of vaginal prostaglandin pessaries on induction of labour and improvement in the favourability of the cervix
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1
Sunderland District General Hospital (England)
Clin. Exp. Obstet. Gynecol. 1984, 11(4), 117–119;
Published: 10 December 1984
Abstract
In a double blind trial of prostaglandin pessaries to induce labour, prostaglandins were successful in 47.5% of primiparous and 70.6% of multiparous patients. Of the 66% who did not go into labour this was successfully induced by artificial rupture of the membranes and oxytocin infusion in all but two cases irrespective of whether or not they received the active compound. This trial suggests that prostaglandin pessaries are a useful and very acceptable way of inducing labour and that although they make the cervix more "favourable" they do not significantly alter the outcome of labour. In the light of their high cost it is time that this method of induction and its timing was re-evaluated.