IMR Press / FBS / Volume 9 / Issue 2 / DOI: 10.2741/S486

Frontiers in Bioscience-Scholar (FBS) is published by IMR Press from Volume 13 Issue 1 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.


Disparity in rates of HPV infection and cervical cancer in underserved US populations

Show Less
1 Department of Pharmaceutical Sciences and Cancer Research Center, University of Tennessee Health Science Center, Memphis, Tennessee, USA, 38163
2 Department of Pathology, University of Tennessee Health Science Center, Memphis, Tennessee, USA, 38163
3 Division of Social and Behavioral Sciences, School of Public Health, University of Memphis, Memphis, TN, 38152

*Author to whom correspondence should be addressed.

Academic Editors: Ajay Pratap Singh, Seema Singh

Front. Biosci. (Schol Ed) 2017, 9(2), 254–269;
Published: 1 June 2017

There is a higher rate of HPV infection and cervical cancer incidence and mortality in underserved US population who reside in Appalachian mountain region compared to Northern Plains. Social and behavioral factors such as smoking and alcohol consumption are for such a high incidence. However, by and large, the reasons for these discrepancies lie in the reluctance of the underserved population to adopt preventive measures such as prophylactic Human papilloma virus (HPV) vaccines and Pap smear screening that have significantly reduced the incidence and mortality rate of cervical cancer in Caucasian women. Thus, it is clear that drastic change in social behavior and implementation of preventive measures is required to effectively reduce the incidence and mortality from cervical cancer in this underserved population.

HPV genotype
Cervical Cancer
Health Disparity
Appalachian women
American Indian
African American
Back to top