Dear Colleagues,

It is our pleasure to inform you about the Special Issue entitled “Genetics and Chronic Disease.” Chronic diseases are defined broadly as conditions that last one year or more and require ongoing medical attention or limit activities of daily living or both. Chronic diseases such as cardiovascular diseases, cancer, diabetes, metabolic bone diseases or neurodegenerative diseases are the leading causes of death and disability worldwide. Eighty-eight percent of subjects over 65 have at least one chronic health condition, while four in ten adults have two or more. They are also leading drivers of high costs in annual health care. Chronic diseases are multifactorial alterations in which genetic and environmental factors are crucial. The most widely accepted etiopathogenic hypothesis is that they are a consequence of the synergic interplay of environmental and genetic factors. Genetic determinations may account for an individual’s susceptibility to developing disease. In this context, this Special Issue focuses on genetic factors associated with the pathogenesis of chronic diseases. We invite researchers to submit original or review articles on basic, translational, and clinical aspects in the genetics associated with the pathogenesis of chronic diseases.

Prof. Dr. José Luis Pérez-Castrillón and Dr. Ricardo Usategui Martín

Guest Editors