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Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.
Volume 13 Issue 2 2008
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Open Access
Article
Molecular imaging of human epidermal growth factor receptor 2 (HER-2) expression
Gang Niu,
Weibo Cai,
Xiaoyuan Chen
Front. Biosci. (Landmark Ed) 2008, 13(2), 790–805;
https://doi.org/10.2741/2720
(This article belongs to the Special Issue Molecular imaging of biomarkers)
7
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22
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9
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Open Access
Article
Development of Alzheimer's disease imaging agents for clinical studies
Eun Kyoung Ryu,
Xiaoyuan Chen
Front. Biosci. (Landmark Ed) 2008, 13(2), 777–789;
https://doi.org/10.2741/2719
(This article belongs to the Special Issue Molecular imaging of biomarkers)
3
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17
Citations
4
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Open Access
Article
Role of Rho GTPases in breast cancer
Yong Tang,
Lola Olufemi,
Man-Tzu Wang,
Daotai Nie
Front. Biosci. (Landmark Ed) 2008, 13(2), 759–776;
https://doi.org/10.2741/2718
(This article belongs to the Special Issue Pathogenesis of tumor progression in breast and prostate cancer)
15
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85
Citations
10
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Open Access
Article
MSPL/TMPRSS13
Hiroshi Kido,
Yuushi Okumura
Front. Biosci. (Landmark Ed) 2008, 13(2), 754–758;
https://doi.org/10.2741/2717
35
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20
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13
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Open Access
Article
Non-proteolytic activation of prorenin: activation by (pro)renin receptor and its inhibition by a prorenin prosegment, "decoy peptide"
M Nasir Uddin,
A H M Nurun Nabi,
Tsutomu Nakagawa,
Atsuhiro Ichihara, ... Fumiaki Suzuki
Front. Biosci. (Landmark Ed) 2008, 13(2), 745–753;
https://doi.org/10.2741/2716
(This article belongs to the Special Issue Renin, prorenin, and prorenin receptor)
3
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9
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6
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Open Access
Article
Targeted gene modification by oligonucleotides and small DNA fragments in eukaryotes
Takayuki Suzuki
Front. Biosci. (Landmark Ed) 2008, 13(2), 737–744;
https://doi.org/10.2741/2715
(This article belongs to the Special Issue Targeted gene repair)
2
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8
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6
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Open Access
Article
The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy
John J. Shacka,
Kevin A. Roth,
Jianhua Zhang
Front. Biosci. (Landmark Ed) 2008, 13(2), 718–736;
https://doi.org/10.2741/2714
(This article belongs to the Special Issue Molecular biology of neurodegeneration)
25
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93
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14
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Open Access
Article
Neuroinflammation in Parkinson's disease: Is there sufficient evidence for mechanism-based interventional therapy?
Malú G. Tansey,
Tamy C. Frank-Cannon,
Melissa K. McCoy,
Jae Kyung Lee, ... Thi A. Tran
Front. Biosci. (Landmark Ed) 2008, 13(2), 709–717;
https://doi.org/10.2741/2713
(This article belongs to the Special Issue Molecular biology of neurodegeneration)
5
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79
Citations
14
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Open Access
Article
Classification algorithms for phenotype prediction in genomics and proteomics
Habtom W. Ressom,
Rency S. Varghese,
Zhen Zhang,
Jianhua Xuan,
Robert Clarke
Front. Biosci. (Landmark Ed) 2008, 13(2), 691–708;
https://doi.org/10.2741/2712
(This article belongs to the Special Issue Classification and prediction in genomics and proteomics)
12
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37
Citations
2
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Open Access
Article
Emergent unsupervised clustering paradigms with potential application to bioinformatics
David J. Miller,
Yue Wang,
George Kesidis
Front. Biosci. (Landmark Ed) 2008, 13(2), 677–690;
https://doi.org/10.2741/2711
(This article belongs to the Special Issue Classification and prediction in genomics and proteomics)
4
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17
Citations
5
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Open Access
Article
Diverse roles of Rho family GTPases in neuronal development, survival, and death
Daniel A. Linseman,
Frances Alexandra Loucks
Front. Biosci. (Landmark Ed) 2008, 13(2), 657–676;
https://doi.org/10.2741/2710
(This article belongs to the Special Issue Molecular biology of neurodegeneration)
10
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101
Citations
14
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Open Access
Article
Quantitative flow cytometric monitoring of invasion of epithelial cells by Mycobacterium tuberculosis
Julie A. Chapeton-Montes,
David F. Plaza,
Carlos A. Barrero,
Manuel A. Patarroyo
Front. Biosci. (Landmark Ed) 2008, 13(2), 650–656;
https://doi.org/10.2741/2709
13
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18
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18
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Open Access
Article
Long-term consequences of maternal smoking and developmental chronic nicotine exposure
Ursula H. Winzer-Serhan
Front. Biosci. (Landmark Ed) 2008, 13(2), 636–649;
https://doi.org/10.2741/2708
(This article belongs to the Special Issue Nicotinic acetylcholine receptors in adult and developing brain)
17
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69
Citations
36
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Open Access
Article
Zymogen activation, inhibition, and ectodomain shedding of matriptase
Chen-Yong Lin,
I-Chu Tseng,
Feng-Pai Chou,
Sheng-Fang Su, ... Robert B. Dickson
Front. Biosci. (Landmark Ed) 2008, 13(2), 621–635;
https://doi.org/10.2741/2707
31
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62
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22
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Open Access
Article
HIV-1 vaccine development: tackling virus diversity with a multi-envelope cocktail
Julia L Hurwitz,
Xiaoyan Zhan,
Scott A Brown,
Mattia Bonsignori, ... Karen S Slobod
Front. Biosci. (Landmark Ed) 2008, 13(2), 609–620;
https://doi.org/10.2741/2706
(This article belongs to the Special Issue Harnessing immune potential by vaccination)
1
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17
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6
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Open Access
Article
Interferon-inducible IFI16 protein in human cancers and autoimmune diseases
Divaker Choubey,
Ranjan Deka,
Shuk-mei Ho
Front. Biosci. (Landmark Ed) 2008, 13(2), 598–608;
https://doi.org/10.2741/2705
(This article belongs to the Special Issue ADAMTS-18: A metalloproteinase with multiple functions)
33
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55
Citations
15
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Open Access
Article
Nuclear diacylglycerol kinases: regulation and roles
Daniel M. Raben,
Becky Tu-Sekine
Front. Biosci. (Landmark Ed) 2008, 13(2), 590–597;
https://doi.org/10.2741/2704
(This article belongs to the Special Issue Nuclear phosphoinositol lipids signaling)
14
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25
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3
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Open Access
Article
TWEAKing renal injury
Ana Belen Sanz,
Juan Antonio Moreno,
Maria Dolores Sanchez-Nino,
Alvaro C Ucero, ... Alberto Ortiz
Front. Biosci. (Landmark Ed) 2008, 13(2), 580–589;
https://doi.org/10.2741/2703
(This article belongs to the Special Issue TWEAK and FN14 in health and disease)
7
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9
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12
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Article
The type II transmembrane serine protease Matriptase-2 – identification, structural features, enzymology, expression pattern and potential roles
Andrew J. Ramsay,
Janet C. Reid,
Gloria Velasco,
James P. Quigley,
John D. Hooper
Front. Biosci. (Landmark Ed) 2008, 13(2), 569–579;
https://doi.org/10.2741/2702
16
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34
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7
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Open Access
Article
Shikonin analogue (SA) 93/637 induces apoptosis by activation of caspase-3 in U937 cells
Rajesh L. Thangapazham,
Anoop K. Singh,
Pankaj Seth,
Namita Misra, ... Radha K. Maheshwari
Front. Biosci. (Landmark Ed) 2008, 13(2), 561–568;
https://doi.org/10.2741/2701
(This article belongs to the Special Issue Cancer chemoprevention - 2)
4
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11
Citations
3
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Open Access
Article
The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis
Constanze Bonifer,
David A. Hume
Front. Biosci. (Landmark Ed) 2008, 13(2), 549–560;
https://doi.org/10.2741/2700
(This article belongs to the Special Issue Biology of the macrophage in human disease)
38
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55
Citations
17
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Open Access
Article
Nuclear phosphoinositide signaling
Keqiang Ye,
Jee-Yin Ahn
Front. Biosci. (Landmark Ed) 2008, 13(2), 540–548;
https://doi.org/10.2741/2699
(This article belongs to the Special Issue Nuclear phosphoinositol lipids signaling)
2
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21
Citations
2
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Open Access
Article
MT-SP1 proteolysis and regulation of cell-microenvironment interactions
Molly R Darragh,
Ami S Bhatt,
Charles S Craik
Front. Biosci. (Landmark Ed) 2008, 13(2), 528–539;
https://doi.org/10.2741/2698
23
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32
Citations
8
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Open Access
Article
Clinical approaches in the treatment of Duchenne muscular dystrophy (DMD) using oligonucleotides
Carmen Bertoni
Front. Biosci. (Landmark Ed) 2008, 13(2), 517–527;
https://doi.org/10.2741/2697
(This article belongs to the Special Issue Targeted gene repair)
6
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22
Citations
8
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Open Access
Article
Gender differences in tobacco smoking dynamics and the neuropharmacological actions of nicotine
James R. Pauly
Front. Biosci. (Landmark Ed) 2008, 13(2), 505–516;
https://doi.org/10.2741/2696
(This article belongs to the Special Issue Nicotinic acetylcholine receptors in adult and developing brain)
19
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47
Citations
15
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Open Access
Article
Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease
Marina R. Picciotto,
Michele Zoli
Front. Biosci. (Landmark Ed) 2008, 13(2), 492–504;
https://doi.org/10.2741/2695
16
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156
Citations
12
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Open Access
Article
Naturally occurring genetic variability in the nicotinic acetylcholine receptor alpha4 and alpha7 subunit genes and phenotypic diversity in humans and mice
Jerry A. Stitzel
Front. Biosci. (Landmark Ed) 2008, 13(2), 477–491;
https://doi.org/10.2741/2694
(This article belongs to the Special Issue Nicotinic acetylcholine receptors in adult and developing brain)
2
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15
Citations
2
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Open Access
Article
New insights into the molecular basis of mammalian sperm-egg membrane interactions
Ulyana Vjugina,
Janice P. Evans
Front. Biosci. (Landmark Ed) 2008, 13(2), 462–476;
https://doi.org/10.2741/2693
(This article belongs to the Special Issue Sperm biology, from basic to clinic)
22
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54
Citations
16
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Open Access
Article
Macrophage activation and polarization
Fernando Oneissi Martinez,
Antonio Sica,
Alberto Mantovani,
Massimo Locati
Front. Biosci. (Landmark Ed) 2008, 13(2), 453–461;
https://doi.org/10.2741/2692
(This article belongs to the Special Issue Lipopolysaccharide signaling and induction of gene expression in monocytes)
1063
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2012
Citations
427
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Open Access
Article
EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer
Sharmila Shankar,
Suthakar Ganapathy,
Sunil R. Hingorani,
Rakesh K. Srivastava
Front. Biosci. (Landmark Ed) 2008, 13(2), 440–452;
https://doi.org/10.2741/2691
(This article belongs to the Special Issue Cancer chemoprevention - 2)
49
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180
Citations
84
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Open Access
Article
Role of P2Y receptor subtypes in platelet-derived microparticle generation
Bryan N. Kahner,
Robert T. Dorsam,
Satya P. Kunapuli
Front. Biosci. (Landmark Ed) 2008, 13(2), 433–439;
https://doi.org/10.2741/2690
(This article belongs to the Special Issue Platelet physiology)
9
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21
Citations
7
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Open Access
Article
Effects of exercise training upon endothelial function in patients with cardiovascular disease
Axel Linke,
Sandra Erbs,
Rainer Hambrecht
Front. Biosci. (Landmark Ed) 2008, 13(2), 424–432;
https://doi.org/10.2741/2689
(This article belongs to the Special Issue Exercise in medicine: from basic science to clinical practice)
28
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47
Citations
39
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Open Access
Article
Molecular pathophysiology and physical chemistry of cholesterol gallstones
Helen H. Wang,
Piero Portincasa,
David Q.-H. Wang
Front. Biosci. (Landmark Ed) 2008, 13(2), 401–423;
https://doi.org/10.2741/2688
(This article belongs to the Special Issue Molecular basis of gallstone pathogenesis)
27
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62
Citations
32
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