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Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.
Volume 13 Issue 2 2008
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- ArticleMolecular imaging of human epidermal growth factor receptor 2 (HER-2) expressionGang Niu, Weibo Cai, Xiaoyuan ChenFront. Biosci. (Landmark Ed) 2008, 13(2), 790–805; https://doi.org/10.2741/2720(This article belongs to the Special Issue Molecular imaging of biomarkers)12Downloads23Citations45Views
- ArticleDevelopment of Alzheimer's disease imaging agents for clinical studiesEun Kyoung Ryu, Xiaoyuan ChenFront. Biosci. (Landmark Ed) 2008, 13(2), 777–789; https://doi.org/10.2741/2719(This article belongs to the Special Issue Molecular imaging of biomarkers)5Downloads17Citations22Views
- ArticleRole of Rho GTPases in breast cancerYong Tang, Lola Olufemi, Man-Tzu Wang, Daotai NieFront. Biosci. (Landmark Ed) 2008, 13(2), 759–776; https://doi.org/10.2741/2718(This article belongs to the Special Issue Pathogenesis of tumor progression in breast and prostate cancer)34Downloads89Citations98Views
- ArticleMSPL/TMPRSS13Hiroshi Kido, Yuushi OkumuraFront. Biosci. (Landmark Ed) 2008, 13(2), 754–758; https://doi.org/10.2741/271746Downloads22Citations41Views
- ArticleNon-proteolytic activation of prorenin: activation by (pro)renin receptor and its inhibition by a prorenin prosegment, "decoy peptide"M Nasir Uddin, A H M Nurun Nabi, Tsutomu Nakagawa, Atsuhiro Ichihara, ... Fumiaki SuzukiFront. Biosci. (Landmark Ed) 2008, 13(2), 745–753; https://doi.org/10.2741/2716(This article belongs to the Special Issue Renin, prorenin, and prorenin receptor)6Downloads10Citations24Views
- ArticleTargeted gene modification by oligonucleotides and small DNA fragments in eukaryotesTakayuki SuzukiFront. Biosci. (Landmark Ed) 2008, 13(2), 737–744; https://doi.org/10.2741/2715(This article belongs to the Special Issue Targeted gene repair)8Downloads8Citations22Views
- ArticleThe autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapyJohn J. Shacka, Kevin A. Roth, Jianhua ZhangFront. Biosci. (Landmark Ed) 2008, 13(2), 718–736; https://doi.org/10.2741/2714(This article belongs to the Special Issue Molecular biology of neurodegeneration)44Downloads98Citations171Views
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Neuroinflammation in Parkinson's disease: Is there sufficient evidence for mechanism-based interventional therapy?
Malú G. Tansey, Tamy C. Frank-Cannon, Melissa K. McCoy, Jae Kyung Lee, ... Thi A. TranFront. Biosci. (Landmark Ed) 2008, 13(2), 709–717; https://doi.org/10.2741/2713(This article belongs to the Special Issue Molecular biology of neurodegeneration)14Downloads85Citations48Views - ArticleClassification algorithms for phenotype prediction in genomics and proteomicsHabtom W. Ressom, Rency S. Varghese, Zhen Zhang, Jianhua Xuan, Robert ClarkeFront. Biosci. (Landmark Ed) 2008, 13(2), 691–708; https://doi.org/10.2741/2712(This article belongs to the Special Issue Classification and prediction in genomics and proteomics)24Downloads41Citations26Views
- ArticleEmergent unsupervised clustering paradigms with potential application to bioinformaticsDavid J. Miller, Yue Wang, George KesidisFront. Biosci. (Landmark Ed) 2008, 13(2), 677–690; https://doi.org/10.2741/2711(This article belongs to the Special Issue Classification and prediction in genomics and proteomics)13Downloads20Citations22Views
- ArticleDiverse roles of Rho family GTPases in neuronal development, survival, and deathDaniel A. Linseman, Frances Alexandra LoucksFront. Biosci. (Landmark Ed) 2008, 13(2), 657–676; https://doi.org/10.2741/2710(This article belongs to the Special Issue Molecular biology of neurodegeneration)27Downloads105Citations47Views
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Quantitative flow cytometric monitoring of invasion of epithelial cells by Mycobacterium tuberculosis
Julie A. Chapeton-Montes, David F. Plaza, Carlos A. Barrero, Manuel A. PatarroyoFront. Biosci. (Landmark Ed) 2008, 13(2), 650–656; https://doi.org/10.2741/270920Downloads18Citations103Views - ArticleLong-term consequences of maternal smoking and developmental chronic nicotine exposureUrsula H. Winzer-SerhanFront. Biosci. (Landmark Ed) 2008, 13(2), 636–649; https://doi.org/10.2741/2708(This article belongs to the Special Issue Nicotinic acetylcholine receptors in adult and developing brain)27Downloads73Citations208Views
- ArticleZymogen activation, inhibition, and ectodomain shedding of matriptaseChen-Yong Lin, I-Chu Tseng, Feng-Pai Chou, Sheng-Fang Su, ... Robert B. DicksonFront. Biosci. (Landmark Ed) 2008, 13(2), 621–635; https://doi.org/10.2741/270758Downloads63Citations112Views
- ArticleHIV-1 vaccine development: tackling virus diversity with a multi-envelope cocktailJulia L Hurwitz, Xiaoyan Zhan, Scott A Brown, Mattia Bonsignori, ... Karen S SlobodFront. Biosci. (Landmark Ed) 2008, 13(2), 609–620; https://doi.org/10.2741/2706(This article belongs to the Special Issue Harnessing immune potential by vaccination)1Downloads16Citations29Views
- ArticleInterferon-inducible IFI16 protein in human cancers and autoimmune diseasesDivaker Choubey, Ranjan Deka, Shuk-mei HoFront. Biosci. (Landmark Ed) 2008, 13(2), 598–608; https://doi.org/10.2741/2705(This article belongs to the Special Issue ADAMTS-18: A metalloproteinase with multiple functions)62Downloads61Citations91Views
- ArticleNuclear diacylglycerol kinases: regulation and rolesDaniel M. Raben, Becky Tu-SekineFront. Biosci. (Landmark Ed) 2008, 13(2), 590–597; https://doi.org/10.2741/2704(This article belongs to the Special Issue Nuclear phosphoinositol lipids signaling)24Downloads25Citations51Views
- ArticleTWEAKing renal injuryAna Belen Sanz, Juan Antonio Moreno, Maria Dolores Sanchez-Nino, Alvaro C Ucero, ... Alberto OrtizFront. Biosci. (Landmark Ed) 2008, 13(2), 580–589; https://doi.org/10.2741/2703(This article belongs to the Special Issue TWEAK and FN14 in health and disease)10Downloads9Citations47Views
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The type II transmembrane serine protease Matriptase-2 – identification, structural features, enzymology, expression pattern and potential roles
Andrew J. Ramsay, Janet C. Reid, Gloria Velasco, James P. Quigley, John D. HooperFront. Biosci. (Landmark Ed) 2008, 13(2), 569–579; https://doi.org/10.2741/270235Downloads36Citations156Views - Article
Shikonin analogue (SA) 93/637 induces apoptosis by activation of caspase-3 in U937 cells
Rajesh L. Thangapazham, Anoop K. Singh, Pankaj Seth, Namita Misra, ... Radha K. MaheshwariFront. Biosci. (Landmark Ed) 2008, 13(2), 561–568; https://doi.org/10.2741/2701(This article belongs to the Special Issue Cancer chemoprevention - 2)4Downloads11Citations7Views - Article
The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis
Constanze Bonifer, David A. HumeFront. Biosci. (Landmark Ed) 2008, 13(2), 549–560; https://doi.org/10.2741/2700(This article belongs to the Special Issue Biology of the macrophage in human disease)81Downloads58Citations80Views - ArticleNuclear phosphoinositide signalingKeqiang Ye, Jee-Yin AhnFront. Biosci. (Landmark Ed) 2008, 13(2), 540–548; https://doi.org/10.2741/2699(This article belongs to the Special Issue Nuclear phosphoinositol lipids signaling)6Downloads22Citations18Views
- ArticleMT-SP1 proteolysis and regulation of cell-microenvironment interactionsMolly R Darragh, Ami S Bhatt, Charles S CraikFront. Biosci. (Landmark Ed) 2008, 13(2), 528–539; https://doi.org/10.2741/269832Downloads34Citations35Views
- ArticleClinical approaches in the treatment of Duchenne muscular dystrophy (DMD) using oligonucleotidesCarmen BertoniFront. Biosci. (Landmark Ed) 2008, 13(2), 517–527; https://doi.org/10.2741/2697(This article belongs to the Special Issue Targeted gene repair)11Downloads24Citations38Views
- ArticleGender differences in tobacco smoking dynamics and the neuropharmacological actions of nicotineJames R. PaulyFront. Biosci. (Landmark Ed) 2008, 13(2), 505–516; https://doi.org/10.2741/2696(This article belongs to the Special Issue Nicotinic acetylcholine receptors in adult and developing brain)24Downloads49Citations118Views
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Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease
Marina R. Picciotto, Michele ZoliFront. Biosci. (Landmark Ed) 2008, 13(2), 492–504; https://doi.org/10.2741/269544Downloads166Citations269Views - ArticleNaturally occurring genetic variability in the nicotinic acetylcholine receptor alpha4 and alpha7 subunit genes and phenotypic diversity in humans and miceJerry A. StitzelFront. Biosci. (Landmark Ed) 2008, 13(2), 477–491; https://doi.org/10.2741/2694(This article belongs to the Special Issue Nicotinic acetylcholine receptors in adult and developing brain)3Downloads17Citations23Views
- ArticleNew insights into the molecular basis of mammalian sperm-egg membrane interactionsUlyana Vjugina, Janice P. EvansFront. Biosci. (Landmark Ed) 2008, 13(2), 462–476; https://doi.org/10.2741/2693(This article belongs to the Special Issue Sperm biology, from basic to clinic)34Downloads60Citations59Views
- ArticleMacrophage activation and polarizationFernando Oneissi Martinez, Antonio Sica, Alberto Mantovani, Massimo LocatiFront. Biosci. (Landmark Ed) 2008, 13(2), 453–461; https://doi.org/10.2741/2692(This article belongs to the Special Issue Lipopolysaccharide signaling and induction of gene expression in monocytes)1722Downloads2233Citations2160Views
- ArticleEGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancerSharmila Shankar, Suthakar Ganapathy, Sunil R. Hingorani, Rakesh K. SrivastavaFront. Biosci. (Landmark Ed) 2008, 13(2), 440–452; https://doi.org/10.2741/2691(This article belongs to the Special Issue Cancer chemoprevention - 2)90Downloads192Citations353Views
- ArticleRole of P2Y receptor subtypes in platelet-derived microparticle generationBryan N. Kahner, Robert T. Dorsam, Satya P. KunapuliFront. Biosci. (Landmark Ed) 2008, 13(2), 433–439; https://doi.org/10.2741/2690(This article belongs to the Special Issue Platelet physiology)10Downloads21Citations16Views
- ArticleEffects of exercise training upon endothelial function in patients with cardiovascular diseaseAxel Linke, Sandra Erbs, Rainer HambrechtFront. Biosci. (Landmark Ed) 2008, 13(2), 424–432; https://doi.org/10.2741/2689(This article belongs to the Special Issue Exercise in medicine: from basic science to clinical practice)38Downloads50Citations193Views
- ArticleMolecular pathophysiology and physical chemistry of cholesterol gallstonesHelen H. Wang, Piero Portincasa, David Q.-H. WangFront. Biosci. (Landmark Ed) 2008, 13(2), 401–423; https://doi.org/10.2741/2688(This article belongs to the Special Issue Molecular basis of gallstone pathogenesis)66Downloads65Citations125Views