Dear Colleagues,

In the last two decades, the “microbiota revolution” has profoundly changed our knowledge in several fields of medicine, offering preclinical and translational evidence on the intriguing network between gut microbiota, inflammation, autoimmunity, and non-communicable diseases. The gut microbiota is now considered a complex organ, at the crossroads of many systems, and involved in both physiological and pathological processes. Therefore, it can be approached as a new model of scientific research and clinical management. In addition, since the microbiota composition is partially modulated by external factors (such as diet, pre-and probiotics, lifestyle, drugs, etc.) this complex organ can be properly preserved and restored when necessary.

Several new organ axes have recently been discovered, including the gut-liver, gut-brain, gut-eye, gut-joint, and gut-muscle axis. The aims of this Special Issue “Gut dysbiosis-associated diseases:unraveling the “gut-other axes” in non-communicable diseases” is to go in-depth into this landscape and offer a broader and complete vision of this subject. This Special Issues is being hosted by Frontiers in Bioscience-Landmark. Original papers, review articles, systematic reviews, and meta-analyses with translational significance are welcomed for this project.

Dr. Emanuele Rinninella

Guest Editor