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Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.
Volume 9 Issue 4 2004
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- Open Access ArticleThe blood brain barrier in HIV infectionJoseph R Berger, Malcolm AvisonFront. Biosci. (Landmark Ed) 2004, 9(4), 2680–2685; https://doi.org/10.2741/1427(This article belongs to the Special Issue Inflammatory disorders of the nervous system)7Download36Citations124Views
- Open Access ArticleGenotypic and phenotypic biomarker profiles for individual risk assessment and cancer detection (lessons from bladder cancer risk assessment in symptomatic patients and workers exposed to benzidine)George P Hemstreet, Wenyu WangFront. Biosci. (Landmark Ed) 2004, 9(4), 2671–2679; https://doi.org/10.2741/1426(This article belongs to the Special Issue Tumor markers for bladder cancer early detection)2Download4Citations4Views
- Open Access ArticleMolecular mechanisms of chemoprevention and therapy of cancer by retinoidsPatrick F ShenFront. Biosci. (Landmark Ed) 2004, 9(4), 2663–2670; https://doi.org/10.2741/14253Download8Citations4Views
- Open Access Article
Copper storage diseases: Menkes, Wilson's, and cancer
Kenyon G Daniel, R Hope Harbach, Wayne C Guida, Q Ping DouFront. Biosci. (Landmark Ed) 2004, 9(4), 2652–2662; https://doi.org/10.2741/1424(This article belongs to the Special Issue Potential molecular targets for chemoprevention)26Download99Citations30Views - Open Access ArticleRegulation of skin cell homeostasis by gamma delta T cellsJulie M Jameson, Leslie L Sharp, Deborah A Witherden, Wendy L HavranFront. Biosci. (Landmark Ed) 2004, 9(4), 2640–2651; https://doi.org/10.2741/1423(This article belongs to the Special Issue Role of unconventional T cells in immune defense)21Download50Citations16Views
- Open Access ArticleSphingolipids in the chemoprevention of colon cancerEva M SchmelzFront. Biosci. (Landmark Ed) 2004, 9(4), 2632–2639; https://doi.org/10.2741/1422(This article belongs to the Special Issue Potential molecular targets for chemoprevention)8Download34Citations8Views
- Open Access ArticleGreen tea and tea polyphenols in cancer preventionDi Chen, Kenyon G Daniel, Deborah J Kuhn, Aslamuzzaman Kazi, ... Q Ping DouFront. Biosci. (Landmark Ed) 2004, 9(4), 2618–2631; https://doi.org/10.2741/1421(This article belongs to the Special Issue Potential molecular targets for chemoprevention)25Download61Citations83Views
- Open Access ArticleBeta-lactams and their potential use as novel anticancer chemotherapeutics drugsDeborah Kuhn, Cristina Coates, Kenyon Daniel, Di Chen, ... Q Ping DouFront. Biosci. (Landmark Ed) 2004, 9(4), 2605–2617; https://doi.org/10.2741/1420(This article belongs to the Special Issue Potential molecular targets for chemoprevention)34Download42Citations19Views
- Open Access ArticleRole of gammadelta T lymphocytes in tumor defenseMaria Raffaella Zocchi, Alessandro PoggiFront. Biosci. (Landmark Ed) 2004, 9(4), 2588–2604; https://doi.org/10.2741/1419(This article belongs to the Special Issue Role of unconventional T cells in immune defense)4Download27Citations9Views
- Open Access ArticleFunctional roles of NKT cell in the immune systemKen-ichiro Seino, Masaru TaniguchiFront. Biosci. (Landmark Ed) 2004, 9(4), 2577–2587; https://doi.org/10.2741/1418(This article belongs to the Special Issue Role of unconventional T cells in immune defense)4Download27Citations6Views
- Open Access ArticleRole of accessory proteins of HTLV-1 in viral replication, T cell activation, and cellular gene expressionMichael Bindhu, Amrithraj Nair, Michael D LairmoreFront. Biosci. (Landmark Ed) 2004, 9(4), 2556–2576; https://doi.org/10.2741/1417(This article belongs to the Special Issue Taking control of the host: molecular strategies of HTLV-I infection)1Download22Citations4Views
- Open Access ArticleDual functional regulators coordinate DNA replication and gene expression in proliferating cellsBik K Tye, Victoria K ChangFront. Biosci. (Landmark Ed) 2004, 9(4), 2548–2555; https://doi.org/10.2741/14163Download8Citations5Views
- Open Access ArticleThe mammalian beta globin origin of DNA replicationMirit I AladjemFront. Biosci. (Landmark Ed) 2004, 9(4), 2540–2547; https://doi.org/10.2741/141520Download13Citations11Views
- Open Access ArticleChemopreventive role of folic acid in colorectal cancerAdhip P N Majumdar, Udayini Kodali, Richard JaszewskiFront. Biosci. (Landmark Ed) 2004, 9(4), 2725–2732; https://doi.org/10.2741/1431(This article belongs to the Special Issue Potential molecular targets for chemoprevention)5Download16Citations9Views
- Open Access ArticleThe role of isoflavones in cancer chemopreventionFazlul H Sarkar, Yiwei LiFront. Biosci. (Landmark Ed) 2004, 9(4), 2714–2724; https://doi.org/10.2741/1430(This article belongs to the Special Issue Potential molecular targets for chemoprevention)6Download76Citations8Views
- Open Access ArticlePrevention of colorectal cancer using COX-2 inhibitors: basic science and clinical applicationsArthur J Chu, Ta-Hsu Chou, Ben D ChenFront. Biosci. (Landmark Ed) 2004, 9(4), 2697–2713; https://doi.org/10.2741/1429(This article belongs to the Special Issue Potential molecular targets for chemoprevention)12Download24Citations9Views
- Open Access ArticleBrain RNA expression in obese vs lean mice after LPS-induced systemic inflammationL Keith Scott, Vidula Vachharajani, Randall L Mynatt, Alireza Minagar, Steven A ConradFront. Biosci. (Landmark Ed) 2004, 9(4), 2686–2696; https://doi.org/10.2741/1428(This article belongs to the Special Issue Inflammatory disorders of the nervous system)8Download8Citations5Views
- Open Access ArticleImmunopathogensis of HTLV-I associated neurologic disease: molecular, histopathologic, and immunologic approachesNorihiro Takenouchi, Karen Yao, Steven JacobsonFront. Biosci. (Landmark Ed) 2004, 9(4), 2527–2539; https://doi.org/10.2741/1414(This article belongs to the Special Issue Taking control of the host: molecular strategies of HTLV-I infection)2Download11Citations6Views
- Open Access ArticleTranslational autoregulation of thymidylate synthase and dihydrofolate reductaseNingwen Tai, John C Schmitz, Jun Liu, Xiukun Lin, ... Edward ChuFront. Biosci. (Landmark Ed) 2004, 9(4), 2521–2526; https://doi.org/10.2741/1413(This article belongs to the Special Issue Thymidylate synthase in biology and cancer treatment)18Download39Citations19Views
- Open Access Article
Navigating novel mechanisms of cellular plasticity with the NAD+ precursor and nutrient nicotinamide
Faqi Li, Zhao Zhong Chong, Kenneth MaieseFront. Biosci. (Landmark Ed) 2004, 9(4), 2500–2520; https://doi.org/10.2741/14122Download27Citations4Views - Open Access ArticleInfectious transmission and replication of human T-cell leukemia virus type 1David Derse, Gisela Heidecker, Michael Mitchell, Shawn Hill, ... Gerald PrinclerFront. Biosci. (Landmark Ed) 2004, 9(4), 2495–2499; https://doi.org/10.2741/1411(This article belongs to the Special Issue Taking control of the host: molecular strategies of HTLV-I infection)11Download16Citations10Views
- Open Access ArticlePharmacogenomics of thymidylate synthase in cancer treatmentPeter V DanenbergFront. Biosci. (Landmark Ed) 2004, 9(4), 2484–2494; https://doi.org/10.2741/1410(This article belongs to the Special Issue Thymidylate synthase in biology and cancer treatment)6Download29Citations2Views
- Open Access ArticleMMPS and TIMPS in ovarian physiology and pathophysiologyShlomit Goldman, Eliezer ShalevFront. Biosci. (Landmark Ed) 2004, 9(4), 2474–2483; https://doi.org/10.2741/1409(This article belongs to the Special Issue Tissue remodeling factors in the physiology and pathophysiologies of the female reproductive tract)27Download80Citations23Views
- Open Access ArticleThymidylate synthase: a critical target in cancer therapy?Youcef M RustumFront. Biosci. (Landmark Ed) 2004, 9(4), 2467–2473; https://doi.org/10.2741/1408(This article belongs to the Special Issue Thymidylate synthase in biology and cancer treatment)14Download36Citations10Views
- Open Access ArticlePassive immunization for immunocontraception: lessons learned from infectious diseasesRajesh K Naz, Changanamkandath RajeshFront. Biosci. (Landmark Ed) 2004, 9(4), 2457–2465; https://doi.org/10.2741/1407(This article belongs to the Special Issue Male reproductive medicine)5Download13Citations12Views
- Open Access ArticleSickness behavior in fever and hypothermiaZoltan Szelenyi, Miklos SzekelyFront. Biosci. (Landmark Ed) 2004, 9(4), 2447–2456; https://doi.org/10.2741/1406(This article belongs to the Special Issue Fever and hypothermia in systemic Inflammation)9Download10Citations11Views
- Open Access ArticleProlyl isomerases in yeastMiguel Arevalo-Rodriguez, Xiaoyun Wu, Steven D Hanes, Joseph HeitmanFront. Biosci. (Landmark Ed) 2004, 9(4), 2420–2446; https://doi.org/10.2741/1405(This article belongs to the Special Issue Prolyl isomerases in cell signaling and diseases)21Download81Citations14Views
- Open Access ArticleFunctional role of acetylcholine in the immune systemToru Hosoi, Yasuyuki NomuraFront. Biosci. (Landmark Ed) 2004, 9(4), 2414–2419; https://doi.org/10.2741/1404(This article belongs to the Special Issue Nonneuronal acetylcholine in normal physiology and pathology)6Download9Citations5Views
- Open Access ArticleRole of viral regulatory and accessory proteins in HIV-1 replicationAnila Seelamgari, Anil Maddukuri, Reem Berro, Cynthia de la Fuente, ... Fatah KashanchiFront. Biosci. (Landmark Ed) 2004, 9(4), 2388–2413; https://doi.org/10.2741/1403(This article belongs to the Special Issue Inflammatory response mechanisms)25Download46Citations115Views
- Open Access ArticleCurrent advances in molecular immunology: reference guide for reviews on molecular vaccinesNarendra ChirmuleFront. Biosci. (Landmark Ed) 2004, 9(4), 2373–2387; https://doi.org/10.2741/1402(This article belongs to the Special Issue Molecular aspects to vaccine design molecular aspects to vaccine design)3Download1Citations5Views