IMR Press / FBL / Volume 9 / Issue 3 / DOI: 10.2741/1400

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Article

Enterococcal virulence - pathogenicity island of E. Faecalis

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1 Department of Ophthalmology, Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma, USA
2 Department of Microbiology and Immunology, Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma, USA
Front. Biosci. (Landmark Ed) 2004, 9(3), 2335–2346; https://doi.org/10.2741/1400
Published: 1 September 2004
Abstract

Enterococcal species, though most commonly regarded as members of the microbial flora of the intestinal tract, have recently emerged as human pathogens of significant concern. The rapid spread of antibiotic resistance among enterococci, which has resulted in strains now being routinely isolated that are resistant to all bactericidal regimens, has prompted considerable interest in investigating the pathogenesis of enterococcal infection, with a view toward deriving new, information-based treatment strategies. This review summarizes major findings on the pathogenesis of enterococcal infection, fits them into a model for the dual lifestyle of enterococci as commensal and pathogen, and integrates into that model a recently discovered pathogenicity island of Enterococcus faecalis.

Keywords
Bacterial pathogenesis
enterococci
pathogenicity island
E. faecalis
review
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