Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.
, Alireza Minagar 2, Steven Conrad 11 Critical Care Medicine, Louisiana State University Health Sciences CenterShreveport, Shreveport, LA
2 Department of Neurology, and Medicine, Louisiana State University Health Sciences CenterShreveport, Shreveport, LA
Abstract
Sepsis associated encephalopathy (SAE) is a poorly understood condition that is associated with severe sepsis and appears to have a negative influence on survival. The incidence of encephalopathy secondary to sepsis is unknown. Amino acid derangements, blood-brain barrier disruption, abnormal neurotransmitters, and direct CNS effect are possible causes of septic encephalopathy. Research has not defined the pathogenesis of SAE.
Keywords
- Sepsis
- Encephalopathy
- Shock
- Septic Shock
- Altered Mental Status
- Review