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- Academic Editor
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†These authors contributed equally.
Background: Myogenin is well known as a crucial transcription factor in
skeletal muscle development, yet its other biological functions remain
unexplored. Previous research showed that myogenin suppresses apoptosis induced
by angiotensin II in human induced pluripotent stem cell-derived cardiomyocytes,
and offered a new perspective on myogenin’s role in cardioprotection. However,
the detailed mechanism of this cardioprotection, especially under oxidative
stress, is still unclear. Methods: In this study, hydrogen peroxide
(H