Academic Editor

Article Metrics

  • Information

  • Download

  • Contents

The authors wish to make the following corrections to this paper [1]:

1. the agent names of Loncastuximab tesirine and Tisotumab vedotin were switched, while the information of the remaining columns remains unaltered;

2. a spelling error in the commercial name of “Zynlonta” was corrected;

3. the stated producer of Kadcyla and Polivy specified to “Genentech” instead of “Roche”;

4. the indication of Loncastuximab tesirine has been specified to “DLBCL”.

The authors apologize for the inconvenience and state that the scientific conclusions of the paper remain unaffected.

Original Table 1.FDA-approved antibody-drug conjugates.
Agent Commercial Name Target Payload Indications Approval year
Gemtuzumab ozogamicin [3] Mylotarg (Pfizer) CD33 Calicheamicin AML 2000/2017 (reapproved)
Brentuximab vedotin [4] Adcetris (Seagen) CD30 MMAE HL & ALCL 2011
Ado-trastuzumab emtansine [5] Kadcyla (Roche) HER2 DM1 Breast cancer 2013
Inotuzumab ozogamicin [6] Besponsa (Pfizer) CD22 Calicheamicin ALL 2017
Moxetumumab pasudotox [7] Lumoxiti (AstraZeneca) CD22 PE38 HCL 2018
Polatuzumab vedotin [8] Polivy (Roche) CD79B MMAE DLBCL 2019
Enfortumab vedotin [9] Padcev (Seagen) Nectin-4 MMAE Urothelial carcinoma 2019
Fam-trastuzumab deruxtecan [10] Enhertu (Daiichi Sankyo) HER2 DXd Breast cancer 2019
Sacituzumab govitecan [11] Trodelvy (Immunomedics) Trop-2 SN38 TNBC 2020
Belantamab mafodotin [12] Blenrep (GlaxoSmithKline) BCMA MMAF Multiple myeloma 2020
Tisotumab vedotin [13] Zylonta (ADC Therapeutics) CD19 PBD Dimer LBCL 2021
Loncastuximab tesirine [14] Tivdak (Genmab/Seagen) TF MMAE Cervical cancer 2021
AML, Acute Myeloid Leukemia; ALCL, Anaplastic Large-Cell Lymphoma; ALL, Acute Lymphocytic Leukemia; HCL, Hairy Cell Leukemia; HER2, Human Epidermal Growth Factor Receptor 2; CD, Cluster of Differentiation; DLBCL, Diffuse Large B-Cell Lymphoma; TNBC, Triple-Negative Breast Cancer; LBCL, Large B-Cell Lymphoma; BCMA, B-Cell Maturation Antigen; TF, Tissue Factor; MMAE, Monomethyl Auristatin E; MMAF, Monomethyl Auristatin F; PBD, Pyrrolobenzodiazepine.
Corrected Table 1.FDA-approved antibody-drug conjugates.
Agent Commercial Name Target Payload Indications Approval Year
Gemtuzumab ozogamicin [3] Mylotarg (Pfizer) CD33 Calicheamicin AML 2000/2017 (reapproved)
Brentuximab vedotin [4] Adcetris (Seagen) CD30 MMAE HL & ALCL 2011
Ado-trastuzumab emtansine [5] Kadcyla (Genentech) HER2 DM1 Breast cancer 2013
Inotuzumab ozogamicin [6] Besponsa (Pfizer) CD22 Calicheamicin ALL 2017
Moxetumumab pasudotox [7] Lumoxiti (AstraZeneca) CD22 PE38 HCL 2018
Polatuzumab vedotin [8] Polivy (Genentech) CD79B MMAE DLBCL 2019
Enfortumab vedotin [9] Padcev (Seagen) Nectin-4 MMAE Urothelial carcinoma 2019
Fam-trastuzumab deruxtecan [10] Enhertu (Daiichi Sankyo) HER2 DXd Breast cancer 2019
Sacituzumab govitecan [11] Trodelvy (Immunomedics) Trop-2 SN38 TNBC 2020
Belantamab mafodotin [12] Blenrep (GlaxoSmithKline) BCMA MMAF Multiple myeloma 2020
Loncastuximab tesirine [13] Zynlonta (ADC Therapeutics) CD19 PBD Dimer DLBCL 2021
Tisotumab vedotin [14] Tivdak (Genmab/Seagen) TF MMAE Cervical cancer 2021
AML, Acute Myeloid Leukemia; ALCL, Anaplastic Large-Cell Lymphoma; ALL, Acute Lymphocytic Leukemia; HCL, Hairy Cell Leukemia; HER2, Human Epidermal Growth Factor Receptor 2; CD, Cluster of Differentiation; DLBCL, Diffuse Large B-Cell Lymphoma; TNBC, Triple-Negative Breast Cancer; LBCL, Large B-Cell Lymphoma; BCMA, B-Cell Maturation Antigen; TF, Tissue Factor; MMAE, Monomethyl Auristatin E; MMAF, Monomethyl Auristatin F; PBD, Pyrrolobenzodiazepine.

Reference

Publisher’s Note: IMR Press stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.