IMR Press / FBL / Volume 23 / Issue 5 / DOI: 10.2741/4620

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.


Impact of chocolate on the cardiovascular health

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1 Human and Clinical Nutrition Unit, Department of Medical Oral and Biotechnological Sciences, “G. D’Annunzio” University, Via Dei Vestini 31, Chieti, 66013, Italy
2 Department of Medicine and Ageing Sciences and Center for Excellence on Ageing and Translational Medicine (CeSI-MeT), “G. D’Annunzio” University and Foundation, Via Luigi Polacchi 11, 66013, Chieti, Italy
3 IRCCS “S. Donato” Hospital, San Donato Milanese, Piazza Edmondo Malan, 20097 Milan, Italy
4 Cardiology Unit, “San Camillo De Lellis” Hospital, Via Isonzo 1, 71043 Manfredonia (Fg), Italy
Front. Biosci. (Landmark Ed) 2018, 23(5), 852–864;
Published: 1 January 2018
(This article belongs to the Special Issue Dietary approaches to prevent chronic-degenerative diseases)

The antioxidants such as polyphenols, especially flavonols, present in large quantitites in cocoa, cause vasodilation, modulate inflammatory markers and cardiovascular health, and possess a range of protective cardiovascular effects. On the other hand, overconsumption of chocolate can lead to tachyarrhythmias, supraventricular tachycardia, atrial fibrillation, ventricular tachycardia and ventricular fibrillation due to its caffeine content. This review describes both the cardioprotective and adverse effects of chocolate and its constituents.

Cardiovascular Risk
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