IMR Press / FBL / Volume 23 / Issue 2 / DOI: 10.2741/4591

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review

Use of non-ionizing electromagnetic fields for the treatment of cancer

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1 Department of Cancer Biology, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA
2 Comprehensive Cancer Center of Wake Forest Baptist Medical Center, Winston-Salem, NC, USA
3 Department of Internal Medicine, Section on Hematology and Oncology, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA
4 Brain Tumor Center of Excellence (BTCOE), Thomas K Hearn, Jr. Brain Tumor Research Center, Comprehensive Cancer Center of Wake Forest Baptist Medical Center, Winston-Salem, NC, USA
5 Department of Radiation Oncology, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA
6 Department of Neurobiology and Anatomy, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA
7 Department of Otolaryngology, Stanford University, Stanford, CA, USA
8 Department of Medical Oncology, Division of Solid Tumor, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA
9 Bioelectronics Department, Ecole des Mines de Saint-Etienne, France
10 Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL, USA
11 Department of Physics, Wake Forest University, Winston-Salem, NC, USA
12 TheraBionic GmbH, Ettlingen, Germany
Front. Biosci. (Landmark Ed) 2018, 23(2), 284–297; https://doi.org/10.2741/4591
Published: 1 January 2018
(This article belongs to the Special Issue Pathogenesis of tumor progression in breast and prostate cancer)
Abstract

Cancer treatment and treatment options are quite limited in circumstances such as when the tumor is inoperable, in brain cancers when the drugs cannot penetrate the blood-brain-barrier, or when there is no tumor-specific target for generation of effective therapeutic antibodies. Despite the fact that electromagnetic fields (EMF) in medicine have been used for therapeutic or diagnostic purposes, the use of non-ionizing EMF for cancer treatment is a new emerging concept. Here we summarize the history of EMF from the 1890’s to the novel and new innovative methods that target and treat cancer by non-ionizing radiation.

Keywords
Radiofrequency
Amplitude-modulation
Cancer
TheraBionic
Novocure
Radiofrequency ablation
History
Radar
Review
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