IMR Press / FBL / Volume 23 / Issue 12 / DOI: 10.2741/4704
Open Access Review

Impact of sugar on the body, brain, and behavior

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1 Laboratory of Neuroimaging, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, 20892, USA
2 Office of Director, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, 20892, USA
Front. Biosci. (Landmark Ed) 2018, 23(12), 2255–2266; https://doi.org/10.2741/4704
Published: 1 June 2018
Abstract

Sugar is highly palatable and rewarding, both in its taste and nutritive input. Excessive sugar consumption, however, may trigger neuroadaptations in the reward system that decouple eating behavior from caloric needs and leads to compulsive overeating. Excessive sugar intake is in turn associated with adverse health conditions, including obesity, metabolic syndrome, and inflammatory diseases. This review aims to use recent evidence to connect sugar’s impact on the body, brain, and behavior to elucidate how and why sugar consumption has been implicated in addictive behaviors and poor health outcomes.

Keywords
Sugar
Addiction
Brain
Eating Behavior
Review
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