Dear Colleagues,

Over the past two decades, significant progress has been achieved in the field of genome sequencing. Non-coding RNAs were among the host of discoveries. Based on their size, non-coding RNAs were classified into small non-coding RNAs and long non-coding RNAs (lncRNAs). Increasingly, studies have shown that both small non-coding RNAs, particularly microRNAs, and lncRNAs play versatile roles in human health. Numerous studies have demonstrated that microRNAs and other non-coding RNAs are involved in diverse human diseases such as cancer, and may serve as a potential target for gene therapy as well as a diagnostic screening tool. To provide a platform for the scientific community, Frontiers in Bioscience-Elite will publish a Special Issue on MicroRNAs and other non-coding RNAs in human health. Both invited and unsolicited manuscripts will be welcome. This special issue will include reviews, research articles, and case studies as well as computational modeling and programing in the following topics, but not limited to:

• Genome-wide identification of microRNAs and lncRNAs associated with human disease using clinical samples, cell lines and/or model animals
• Functional analysis of microRNAs and other non-coding RNAs associated with human health
• Drug target identification and health treatment
• MicroRNAs and other non-coding RNAs as targets for drug development
• Genome editing application on non-coding RNAs

Prof. Baohong Zhang

Guest Editor