Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.
Evaluation of unintended electrical stimulation from MR gradient fields
*Author to whom correspondence should be addressed.
Exposure of patients with active implants (e.g. cardiac pacemakers and neurostimulators) to magnetic gradient fields (kHz range) during magnetic resonance imaging presents safety issues, such as unintended stimulation. Magnetically induced electric fields generate currents along the implant’s lead, especially high at the distal tip. Experimental evaluation of the induced electric field was previously conducted. This study aimed to perform the same evaluation by means of computational methods, using two commercially available software packages (SemcadX and COMSOL Multiphysics). Electric field values were analyzed 1-3 mm from the distal tip. The effect of the two-electrode experimental probe was evaluated. The results were compared with previously published experimental data with reasonable agreement at locations more than 2-3 mm from the distal tip of the lead. The results were affected by the computational mesh size, with up to one order of magnitude difference for SEMCAD (resolution of 0.1 mm) compared to COMSOL (resolution of 0.5 mm). The results were also affected by the dimensions of the two-electrode probe, suggesting careful selection of the probe dimensions during experimental studies.