Revista de Neurología (RN) is published by IMR Press from Volume 79 Issue 11 (2024). Previous articles were published by under the CC-BY-NC-ND licence, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement.
Citicoline: pharmacological and clinical review, 2022 update
, P Gareri 21 Departamento Médico. Ferrer, 08028 Barcelona, España
2 Center for Cognitive Disorders and Dementia - Catanzaro Lido, Catanzaro, Italia
*Corresponding author: Dr. Julio J. Secades. Medical Department. Grupo Ferrer, S.A. Avda. Diagonal, 549. E-08029 Barcelona.
E-mail: secades@ferrergrupo.com
Abstract
This review is based on the previous one published in 2016 (Secades JJ. Citicoline: pharmacological and clinical review, 2016 update. Rev Neurol 2016; 63 (Supl 3): S1-S73), incorporating 176 new references, having all the information available in the same document to facilitate the access to the information in one document. This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved the most important experimental and clinical data in both indications.
Keywords
- Alcoholism
- Alzheimer disease
- Amblyopia
- Apoptosis
- CDP-choline
- Cerebral edema
- Cerebral ischemia
- Citicoline
- Cognitive disorder
- Drug addiction
- Glaucoma
- Head injury
- Memory
- Neuronal membrane
- Neuroplasticity
- Neuroprotection
- Neurorepair
- Neurotransmission
- Parkinson disease
- Phosphatidylcholine
- Phospholipase
- Remyelination
- Senile dementia
- Stroke
- Structural phospholipids
- Traumatic brain injury