- Academic Editor
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Microvascular obstruction (MVO) of coronary arteries promotes an increase in
mortality and major adverse cardiac events in patients with acute myocardial
infarction (AMI) and percutaneous coronary intervention (PCI). Intramyocardial
hemorrhage (IMH) is observed in 41–50% of patients with ST-segment elevation
myocardial infarction and PCI. The occurrence of IMH is accompanied by
inflammation. There is evidence that microthrombi are not involved in the
development of MVO. The appearance of MVO is associated with infarct size, the
duration of ischemia of the heart, and myocardial edema. However, there is no
conclusive evidence that myocardial edema plays an important role in the
development of MVO. There is evidence that platelets, inflammation, Ca