- Academic Editor
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Background: The MitraClip G4 system is the latest version of the
transcatheter edge-to-edge repair (TEER) system for mitral regurgitation (MR). We
aimed to investigate the impact of the new system on routine clinical practice
and patient outcomes in the treatment of primary MR. Methods:
Consecutive patients with primary MR who
underwent TEER with either the MitraClip G2 or G4 between 2018 and 2021 were
enrolled from a single center registry. Baseline clinical and echocardiographic
characteristics as well as procedural and clinical outcomes up to 1 year were
compared between groups. Technical and device success were defined in accordance
with the Mitral Valve Academic Research Consortium criteria. Results:
Among 71 patients with primary MR, 34 were treated with G2 and 37 were treated
with G4. Patients treated with G4 had lower surgical risk (7.74 [5.04, 14.97] vs.
5.26 [3.98, 6.40]; p