- Academic Editors
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Background: Most acute coronary syndromes occur due to coronary
thrombosis caused by plaque rupture (PR) and plaque erosion (PE). Precise in vivo
differentiation between PR and PE is challenging for intravascular imaging. This
study is the first to determine the diagnostic performance of the novel 60 MHz
high-definition intravascular ultrasound (HD-IVUS) for differentiating
atherosclerotic plaque morphology influenced by local hemodynamic flow in
rabbits. This study evaluated the diagnostic performance of 60 MHz HD-IVUS in
identifying thrombosis in rabbits. Methods: We established 60 rabbit
models of atherosclerosis with left common carotid artery (LCCA) stenosis and 30
FeCl