IMR Press / RCM / Volume 23 / Issue 9 / DOI: 10.31083/j.rcm2309290
Open Access Review
Coronary Artery Disease and Revascularization in Patients Undergoing Transcatheter Aortic Valve Replacement
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1 Division of Cardiology, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA
2 Division of Cardiology, Tucson Medical Center, Tucson, AZ 85712, USA
*Correspondence: jabbott@lifespan.org (J. Dawn Abbott)
These authors contributed equally.
Academic Editor: Manuel Martínez-Sellés
Rev. Cardiovasc. Med. 2022, 23(9), 290; https://doi.org/10.31083/j.rcm2309290
Submitted: 14 April 2022 | Revised: 18 July 2022 | Accepted: 1 August 2022 | Published: 22 August 2022
(This article belongs to the Special Issue Structural Heart Interventions)
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract

Coronary artery disease (CAD) and aortic stenosis share similar risk factors and underlying pathophysiology. Up to half of the patient population undergoing work-up for aortic valve replacement have underlying CAD, which can affect outcomes in patients with more severe disease. As the indications for transcatheter aortic valve replacement (TAVR) have expanded to intermediate and now low risk patients, the optimal management of CAD in this patient population still needs to be determined. This includes both pre-TAVR evaluation for CAD as well as indications for revascularization in patients undergoing TAVR. There is also limited data on coronary interventions after TAVR, including the incidence, feasibility and outcomes of patients undergoing percutaneous coronary intervention (PCI) after TAVR. This review provides an updated report of the current literature on CAD in TAVR patients, focusing on its prevalence, impact on outcomes, timing of revascularization and potential challenges with coronary interventions post-TAVR.

Keywords
aortic stenosis
coronary artery disease
percutaneous coronary intervention
transcatheter aortic valve replacement
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