†These authors contributed equally.
Academic Editor: Jinnette D. Abbott
Background: Hypertrophic obstructive cardiomyopathy
(HOCM) with severe mitral regurgitation (MR) remains controversial for the choice
of the concomitant mitral valve (MV) management versus septal myectomy alone. The
impacts of different surgical strategies (concomitant mitral subvalvular
procedures versus myectomy alone) on one-year results of surgical treatment of
HOCM with grade 3 to 4+ MR without intrinsic MV disease were evaluated in this
single-center, retrospective observational study. Methods: A total of
146 eligible patients were retrospectively screened into a combined group (n =
40) and an alone group (n = 106), depending on whether they underwent transaortic
mitral subvalvular procedures. Perioperative outcomes were collected, and results
at 1-year following surgery were compared. Results: Surgical mortality
did not differ (0 for combined group vs. 0.9% for alone group, p =
0.538). Six patients (5.0% vs. 3.8%, p = 0.666) developed
postoperative complete atrioventricular node block with permanent pacemaker
implantation. No death or reoperation was recorded during a median follow-up of
18 months. At 1-year following surgery, (1) the provoked MR severity decreased
from baseline in both groups with a significant difference between groups [1.0
(0–1.0) vs. 1.0 (1.0–1.3), p