IMR Press / RCM / Volume 23 / Issue 8 / DOI: 10.31083/j.rcm2308274
Open Access Review
Biological Surgical Options in Young Patients for the Treatment of Severe Aortic Stenosis: Is the Jury Still Out? A Review
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1 Department of Cardiac Surgery, Centre Hospitalier de l’université de Montréal (CHUM), Montreal, QC H2X 0C1, Canada
2 Department of Surgery, Faculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada
*Correspondence: (Jessica Forcillo)
These authors contributed equally.
Academic Editor: Giuseppe Santarpino
Rev. Cardiovasc. Med. 2022, 23(8), 274;
Submitted: 26 May 2022 | Revised: 23 June 2022 | Accepted: 28 June 2022 | Published: 26 July 2022
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.

Aortic interventions remain the most effective treatment for severe aortic stenosis. In the recent years, advances in bioprosthetics and newer data have reduced the cut-off age for the use of bioprosthetic valves in younger patients, but the debate on whether to favor mechanical valves in younger patients remains a constant, especially with the undesired effects and considerations of anticoagulation therapy with vitamin K antagonists in this age group. Other options like the Ross procedure are gaining traction, despite still being undervalued and necessitating expertise centers. Hemodynamic considerations and durability of these options are important to consider, especially in this age group. Regardless of the choice of the prosthesis, patient informed consent is paramount since the decision affects the lifetime management of their initial condition, and expectations given must remain realistic.

aortic stenosis
young adults
aortic valve replacement
bioprosthetic valve
mechanical valve
ross procedure
Fig. 1.
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